Presystemic metabolism and intestinal absorption of antipsoriatic fumaric acid esters
D Werdenberg, R Joshi, S Wolffram… - … & drug disposition, 2003 - Wiley Online Library
Psoriasis is a chronic inflammatory skin disease. Its treatment is based on the inhibition of
proliferation of epidermal cells and interference in the inflammatory process. A new systemic …
proliferation of epidermal cells and interference in the inflammatory process. A new systemic …
Synthesis of peptidyl fluoromethyl ketones and peptidyl. alpha.-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human …
NP Peet, JP Burkhart, MR Angelastro… - Journal of medicinal …, 1990 - ACS Publications
Comparison of MeO-Suc-Val-Pro-Phe-C02Me (29) and MeO-Suc-Ala-Ala-Pro-Phe-C02Me
(25) with their corresponding trifluoromethyl ketones 9a and 9b, respectively, in ratand …
(25) with their corresponding trifluoromethyl ketones 9a and 9b, respectively, in ratand …
Synthesis of α-Keto Acids via Oxidation of Alkenes Catalyzed by a Bifunctional Iron Nanocomposite
T Song, Z Ma, X Wang, Y Yang - Organic Letters, 2021 - ACS Publications
An efficient methodology for synthesis of α-keto acids via oxidation of alkenes using TBHP
as oxidant catalyzed by a bifunctional iron nanocomposite has been established. A variety of …
as oxidant catalyzed by a bifunctional iron nanocomposite has been established. A variety of …
An efficient synthesis of novel. alpha.-diketone and. alpha.-keto ester derivatives of N-protected amino acids and peptides
MR Angelastro, NP Peet, P Bey - The Journal of Organic …, 1989 - ACS Publications
A novel synthetic approach to-diketone and-keto ester derivativesof N-protected amino acids
and peptides via a common intermediate is described. Conversion of the carboxyl group of …
and peptides via a common intermediate is described. Conversion of the carboxyl group of …
Oxidation of α-hydroxy esters to α-keto esters using the Dess-Martin periodinane reagent
JP Burkhart, NP Peet, P Bey - Tetrahedron letters, 1988 - Elsevier
Tetrahedron Letters,Vol.29,No.28,pp 3433-3436,1988 0040-4039,'88 $3.00 + .OO Printed in
Great Britain Pergamon Press plc Page 1 Tetrahedron Letters,Vol.29,No.28,pp 3433-3436,1988 …
Great Britain Pergamon Press plc Page 1 Tetrahedron Letters,Vol.29,No.28,pp 3433-3436,1988 …
Inhibition of chicken liver carboxylesterase by activated carbonyls and carbonyl hydrates
MC Berndt, MR Bowles, GJ King, B Zerner - Biochimica et Biophysica Acta …, 1996 - Elsevier
Identical kcat values (≈ 40 s− 1) are obtained for the chicken liver carboxylesterase
catalyzed hydrolysis of phenyl, p-nitrophenyl and o-nitrophenyl benzoates providing support …
catalyzed hydrolysis of phenyl, p-nitrophenyl and o-nitrophenyl benzoates providing support …
Reactions of Aldehydes and Ketones and their Derivatives
B Capon - Organic Reaction Mechanisms 1973 Reprint A: An …, 2008 - books.google.com
Two mechanisms are possible for the spontaneous hydrolysis of acetals derived from
salicylic acid: ¹ either there is an intramolecularly general-acid catalysed reaction of the un …
salicylic acid: ¹ either there is an intramolecularly general-acid catalysed reaction of the un …
氯化钴/吡嗪-2-羧酸钾体系催化苄基氯双羰化合成β-苄基-α-苯丙酮酸
朱康玲, 李美清, 李琳, 吴方勇, 李光兴 - 催化学报, 2005 - cjcatal.com
将新型氯化钴/吡嗪-2-羧酸钾催化体系用于苄基氯双羰化反应, 并对反应条件进行了优化.
结果表明, 最佳反应条件为: 氯化钴浓度0.03 mol/L, 吡嗪-2-羧酸(Pzca) 浓度0.156 mol/L, n …
结果表明, 最佳反应条件为: 氯化钴浓度0.03 mol/L, 吡嗪-2-羧酸(Pzca) 浓度0.156 mol/L, n …
New catalytic roles for serine esterases: a 19F-NMR study of the interaction of 3, 3, 3-trifluoro-2, 2-dihydroxy-l-phenyl-l-propanone with chicken liver carboxylesterase
MR Bowles, GJ King, MC Berndt, B Zerner - Biochimica et Biophysica Acta …, 1996 - Elsevier
The reactions of 3, 3, 3--trifluoro-2, 2-dihydroxy-l-phenyl-l-propanone (TDPP [with chicken
liver carboxylesterase have shown that this ketone hydrate is not only a potent inhibitor of …
liver carboxylesterase have shown that this ketone hydrate is not only a potent inhibitor of …
Reactions of Acids and their Derivatives
WJ Spillane - Organic Reaction Mechanisms· 1995: An Annual …, 1997 - Wiley Online Library
Semiempirical molecular orbital (PM3) calculations have been reported for the reactions of
m-nitro-, p-nitro-, and 3, 4-dinitro-phenyl formates (1) with 18 phenolate anions in the gas …
m-nitro-, p-nitro-, and 3, 4-dinitro-phenyl formates (1) with 18 phenolate anions in the gas …