From classical to deep learning: review on cartilage and bone segmentation techniques in knee osteoarthritis research

HS Gan, MH Ramlee, AA Wahab, YS Lee… - Artificial Intelligence …, 2021 - Springer
Knee osteoarthritis is a major diarthrodial joint disorder with profound global socioeconomic
impact. Diagnostic imaging using magnetic resonance image can produce morphometric …

Expediting finite element analyses for subject-specific studies of knee osteoarthritis: a literature review

A Paz, GA Orozco, RK Korhonen, JJ García… - Applied Sciences, 2021 - mdpi.com
Osteoarthritis (OA) is a degenerative disease that affects the synovial joints, especially the
knee joint, diminishing the ability of patients to perform daily physical activities …

The future of in-field sports biomechanics: wearables plus modelling compute real-time in vivo tissue loading to prevent and repair musculoskeletal injuries

D Lloyd - Sports Biomechanics, 2021 - Taylor & Francis
This paper explores the use of biomechanics in identifying the mechanistic causes of
musculoskeletal tissue injury and degeneration. It appraises how biomechanics has been …

Atlas-based finite element analyses with simpler constitutive models predict personalized progression of knee osteoarthritis: data from the osteoarthritis initiative

ME Mononen, A Paz, MK Liukkonen, MJ Turunen - Scientific Reports, 2023 - nature.com
New technologies are required to support a radical shift towards preventive healthcare. Here
we focus on evaluating the possibility of finite element (FE) analysis-aided prevention of …

EMG-assisted muscle force driven finite element model of the knee joint with fibril-reinforced poroelastic cartilages and menisci

A Esrafilian, L Stenroth, ME Mononen, P Tanska… - Scientific reports, 2020 - nature.com
Abnormal mechanical loading is essential in the onset and progression of knee
osteoarthritis. Combined musculoskeletal (MS) and finite element (FE) modeling is a typical …

A chemo-mechano-biological modeling framework for cartilage evolving in health, disease, injury, and treatment

MM Rahman, PN Watton, CP Neu, DM Pierce - Computer Methods and …, 2023 - Elsevier
Abstract Background and Objective Osteoarthritis (OA) is a pervasive and debilitating
disease, wherein degeneration of cartilage features prominently. Despite extensive …

An EMG-assisted muscle-force driven finite element analysis pipeline to investigate joint-and tissue-level mechanical responses in functional activities: towards a …

A Esrafilian, L Stenroth, ME Mononen… - IEEE Transactions …, 2022 - ieeexplore.ieee.org
Joint tissue mechanics (eg, stress and strain) are believed to have a major involvement in
the onset and progression of musculoskeletal disorders, eg, knee osteoarthritis (KOA) …

Prediction of local fixed charge density loss in cartilage following ACL injury and reconstruction: a computational proof‐of‐concept study with MRI follow‐up

GA Orozco, P Bolcos, A Mohammadi… - Journal of …, 2021 - Wiley Online Library
The purpose of this proof‐of‐concept study was to develop three‐dimensional patient‐
specific mechanobiological knee joint models to simulate alterations in the fixed charged …

Engineering aspects of incidence, prevalence, and management of osteoarthritis: a review

DK Verma, P Kumari, S Kanagaraj - Annals of Biomedical Engineering, 2022 - Springer
The knee is the biggest and complicated lower extremity joint that supports mobility and the
entire weight of the human body and lies between the hip joint and ankle joint. Osteoarthritis …

Prediction of knee joint compartmental loading maxima utilizing simple subject characteristics and neural networks

J Lavikainen, L Stenroth, T Alkjær… - Annals of biomedical …, 2023 - Springer
Joint loading may affect the development of osteoarthritis, but patient-specific load
estimation requires cumbersome motion laboratory equipment. This reliance could be …