The essential amino acid tryptophan (Trp) is metabolized by gut commensals, yielding in
compounds that affect innate immune cell functions directly, but also acting on the aryl …

Skin barrier dysfunction caused by endogenous or exogenous factors can lead to various
disorders such as xerosis cutis, ichthyoses, and atopic dermatitis. Filaggrin is a pivotal …

Flavonoids are polyphenolic phytochemicals produced in fruits, nuts and vegetables and
dietary consumption of these structurally diverse compounds is associated with multiple …

The aryl hydrocarbon receptor (AhR), discovered 46 years ago, is a transcript factor member
of the basic helix-loop-helix Per-ARNT-SIM (bHLH-PAS) family deeply implicated in health …

The aryl hydrocarbon receptor (AHR) is a transcription factor with roles in detoxification,
development, immune response, chronic kidney disease and other syndromes. It regulates …

The aryl hydrocarbon receptor (AHR) is a member of the basic helix-loop-helix/Per-ARNT-
Sim (bHLH-PAS) family of transcription factors and has broad biological functions. Early after …

Highlights•AhR is an ubiquitous transcription factor activated by a broad spectrum of
endogenous and exogenous ligands.•Sustained AhR activation promotes immune …

Prospective epidemiological studies concur in an association between habitual coffee
consumption and a lower risk of type 2 diabetes. Several aspects of these studies support a …

Simple Summary The aryl hydrocarbon receptor (AhR) is expressed in breast cancer cells
and tumors and in some studies, the AhR is a negative prognostic factor for patient survival …

The aryl hydrocarbon receptor (AHR) is a cytoplasmic transcription factor that is well-known
for regulating xenobiotic metabolism. Studies in knockout and transgenic mice indicate that …