The Role of Endocrine Disruption Chemical-Regulated Aryl Hydrocarbon Receptor Activity in the Pathogenesis of Pancreatic Diseases and Cancer
K Kim - International Journal of Molecular Sciences, 2024 - mdpi.com
The aryl hydrocarbon receptor (AHR) serves as a ligand-activated transcription factor crucial
for regulating fundamental cellular and molecular processes, such as xenobiotic …
for regulating fundamental cellular and molecular processes, such as xenobiotic …
Jian-Pi-Yi-Shen Formula Improves Adenine-Induced Chronic Kidney Disease via Regulating Tryptophan Metabolism and Aryl Hydrocarbon Receptor Signaling
X Liu, R Deng, Y Chen, S Huang, J Lu… - Frontiers in …, 2022 - frontiersin.org
Traditional Chinese medicine (TCM) is an important complementary and alternative branch
of chronic kidney disease (CKD) therapy. Jian-Pi-Yi-Shen formula (JPYSF) is a TCM formula …
of chronic kidney disease (CKD) therapy. Jian-Pi-Yi-Shen formula (JPYSF) is a TCM formula …
Investigating the Aryl Hydrocarbon Receptor Agonist/Antagonist Conformational Switch Using Well-Tempered Metadynamics Simulations
FES Mosa, S AlRawashdeh, AOS El-Kadi… - Journal of Chemical …, 2024 - ACS Publications
The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that mediates
biological signals to control various complicated cellular functions. It plays a crucial role in …
biological signals to control various complicated cellular functions. It plays a crucial role in …
Herbal plants: the role of AhR in mediating immunomodulation
The prevalence of chronic inflammatory diseases including inflammatory bowel disease
(IBD), autoimmunity and cancer have increased in recent years. Herbal-based compounds …
(IBD), autoimmunity and cancer have increased in recent years. Herbal-based compounds …
Role of hepatic aryl hydrocarbon receptor in non-alcoholic fatty liver disease
NY Patil, JE Friedman, AD Joshi - Receptors, 2023 - mdpi.com
Numerous nuclear receptors including farnesoid X receptor, liver X receptor, peroxisome
proliferator-activated receptors, pregnane X receptor, hepatic nuclear factors have been …
proliferator-activated receptors, pregnane X receptor, hepatic nuclear factors have been …
The environmental pollutant, polychlorinated biphenyl 126, alters liver function in a rodent model of alcohol‐associated liver disease
TC Gripshover, B Wahlang, KZ Head… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Background The prevalence of alcohol‐associated liver disease (ALD), a subtype of fatty
liver disease (FLD), continues to rise. ALD is a major cause of preventable death …
liver disease (FLD), continues to rise. ALD is a major cause of preventable death …
Aryl hydrocarbon receptor (AhR)-mediated signaling as a critical regulator of skeletal cell biology
DW Alhamad, H Bensreti, J Dorn… - Journal of …, 2022 - jme.bioscientifica.com
The aryl hydrocarbon receptor (AhR) has been implicated in regulating skeletal progenitor
cells and the activity of bone-forming osteoblasts and bone-resorbing osteoclasts, thereby …
cells and the activity of bone-forming osteoblasts and bone-resorbing osteoclasts, thereby …
[HTML][HTML] Ongoing clinical trials in aging-related tissue fibrosis and new findings related to AhR pathways
HX Yu, Z Feng, W Lin, K Yang, RQ Liu, JQ Li… - Aging and …, 2022 - ncbi.nlm.nih.gov
Fibrosis is a pathological manifestation of wound healing that replaces dead/damaged
tissue with collagen-rich scar tissue to maintain homeostasis, and complications from …
tissue with collagen-rich scar tissue to maintain homeostasis, and complications from …
3, 3′-diindolylmethane and 1, 4-dihydroxy-2-naphthoic acid prevent chronic mild stress induced depressive-like behaviors in female mice
CA Madison, J Kuempel, GL Albrecht, L Hillbrick… - Journal of affective …, 2022 - Elsevier
Background Current pharmaceutical treatments for depression are sometimes ineffective
and may have unwanted side effects that interfere with patient compliance. This study …
and may have unwanted side effects that interfere with patient compliance. This study …
The role of tryptophan in Chlamydia trachomatis persistence
L Wang, YL Hou, HX Yuan, H Chen - Frontiers in Cellular and …, 2022 - frontiersin.org
Chlamydia trachomatis (C. trachomatis) is the most common etiological agent of bacterial
sexually transmitted infections (STIs) and a worldwide public health issue. The natural …
sexually transmitted infections (STIs) and a worldwide public health issue. The natural …