[HTML][HTML] Immunomodulatory drug discovery from herbal medicines: Insights from organ-specific activity and xenobiotic defenses

J Shi, JH Weng, TJ Mitchison - Elife, 2021 - elifesciences.org
Traditional herbal medicines, which emphasize a holistic, patient-centric view of disease
treatment, provide an exciting starting point for discovery of new immunomodulatory drugs …

Oligosaccharides from traditional Chinese herbal medicines: A review of chemical diversity and biological activities

M Liu, M Cai, P Ding - The American journal of Chinese medicine, 2021 - World Scientific
Most of traditional Chinese herbal medicine (TCHM) substances come from medicinal
plants, among which oligosaccharides have gradually attracted widespread attention at …

Ginsenoside Rb1 inhibits cardiomyocyte autophagy via PI3K/Akt/mTOR signaling pathway and reduces myocardial ischemia/reperfusion injury

GW Qin, P Lu, L Peng, W Jiang - The American Journal of Chinese …, 2021 - World Scientific
Myocardial ischemia/reperfusion injury (MIRI) is the major cause of myocardial cell damage
in acute myocardial infarction, and its treatment remains a clinical challenge. Ginsenoside …

Red ginseng protects against cisplatin-induced intestinal toxicity by inhibiting apoptosis and autophagy via the PI3K/AKT and MAPK signaling pathways

J Zhang, J Wang, X Xu, J Yang, Z Wang, S Jiang… - Food & Function, 2020 - pubs.rsc.org
Although growing evidence has shown that ginseng (Panax ginseng CA Meyer.) exerts
strong protective and preventive effects on cisplatin-induced side effects, including …

Berberine and ginsenoside Rb1 ameliorate depression-like behavior in diabetic rats

JH Zhang, HZ Yang, H Su, J Song, Y Bai… - The American Journal …, 2021 - World Scientific
Rhizoma coptidis (Huang-lian) and Asian ginseng have been widely used in the treatment of
diabetes and other concurrent diseases with apparent effects. This study investigated the …

Ginsenoside Rh1 improves type 2 diabetic nephropathy through AMPK/PI3K/Akt-mediated inflammation and apoptosis signaling pathway

WY Su, Y Li, X Chen, X Li, H Wei, Z Liu… - The American Journal …, 2021 - World Scientific
Although ginseng (Panax ginseng CA Meyer) has received extensive attention in the
treatment and prevention of type 2 diabetes mellitus (T2DM) in the past few decades, there …

[HTML][HTML] Sanghuangporus sanghuang Mycelium Prevents Paracetamol-Induced Hepatotoxicity through Regulating the MAPK/NF-κB, Keap1/Nrf2/HO-1, TLR4/PI3K …

WP Jiang, JS Deng, SS Huang, SH Wu, CC Chen… - Antioxidants, 2021 - mdpi.com
Liver damage induced by paracetamol overdose is the main cause of acute liver failure
worldwide. In order to study the hepatoprotective effect of Sanghuangporus sanghuang …

20(S)-Ginsenoside Rg3 Inhibits Lung Cancer Cell Proliferation by Targeting EGFR-Mediated Ras/Raf/MEK/ERK Pathway

Y Liang, T Zhang, S Jing, P Zuo, T Li… - The American Journal …, 2021 - World Scientific
Lung cancer is the leading cause of cancer death in the world and classified into non-small
cell lung cancer (NSCLC) and small cell lung cancer (SCLC). As tyrosine kinase inhibitors …

Ginsenoside Rb1 alleviated concanavalin A-induced hepatocyte pyroptosis by activating mitophagy

Q Zhang, J Hu, A Mao, M Liu, S Guan, J Lu - Food & Function, 2023 - pubs.rsc.org
Pyroptosis is characterized as gasdermin-mediated programmed death and has received
substantial attention in recent years. Excessive hepatocyte pyroptosis could induce acute …

[PDF][PDF] The promising therapeutic potentials of ginsenosides mediated through p38 MAPK signaling inhibition

ESA Arafa, MS Refaey, OAM Abd El-Ghafar… - Heliyon, 2021 - cell.com
The p38 mitogen-activated protein kinases (p38 MAPK) is a 38kD polypeptide recognized
as the target for many potential anti-inflammatory agents. Accumulating evidence indicates …