Plasma protein and venous thromboembolism: prospective cohort and mendelian randomisation analyses

S Yuan, OE Titova, K Zhang, W Gou… - British Journal of …, 2023 - Wiley Online Library
We conducted cohort and Mendelian randomisation (MR) analyses to examine the
associations of circulating proteins with risk of venous thromboembolism (VTE) to provide …

TMT and PRM Based Quantitative Proteomics to Explore the Protective Role and Mechanism of Iristectorin B in Stroke

M Zheng, M Zhou, T Lu, Y Lu, P Qin, C Liu - International Journal of …, 2023 - mdpi.com
Stroke is a serious disease caused by the rupture or blockage of the cerebrovascular
system. Its pathogenesis is complex and involves multiple mechanisms. Iristectorin B is a …

Optimization of High-Activity earthworm fibrinolytic enzyme extraction methods and protein component analysis

Z Zhao, Z Liu, Q Jiang, X Zhang, W Ma… - Journal of Chromatography …, 2024 - Elsevier
Objective Optimize the extraction process of earthworm fibrinolytic enzyme. Methods
Chinese common earthworms underwent a series of purification processes, including …

Discovery of protein biomarkers for venous thromboembolism in non-small cell lung cancer patients through data-independent acquisition mass spectrometry

Y Liu, L Gao, Y Fan, R Ma, Y An, G Chen… - Frontiers in …, 2023 - frontiersin.org
Objective Non-small cell lung cancer (NSCLC) patients present a high incidence of venous
thromboembolism (VTE) with poor prognosis. It is crucial to identify and diagnose VTE early …

Different strokes, different thrombus proteomes

JE Aslan - Journal of Thrombosis and Haemostasis, 2023 - jthjournal.org
Acute ischemic stroke results from thrombus formation and occlusion of cerebral arteries,
representing a leading cause of death and disability around the globe [1]. A number of …

[HTML][HTML] Identifying novel biomarkers using proteomics to predict cancer-associated thrombosis

MJF Turizo, R Patell, JI Zwicker - Bleeding, thrombosis and …, 2024 - ncbi.nlm.nih.gov
Comprehensive protein analyses of plasma are made possible by high-throughput
proteomic screens, which may help find new therapeutic targets and diagnostic biomarkers …

[PDF][PDF] 蛋白质组学在急性冠脉综合征中的应用进展

曹浩然, 万智 - 临床急诊杂志, 2023 - lcjz.whuhzzs.com
急性冠脉综合征(acutecoronarysyndrome, ACS) 是最危险的冠心病类型之一,
有着较高的发病率和死亡率. 传统的生物标志物在ACS 的诊断, 治疗, 预等方面发挥了重要的 …

[HTML][HTML] Влияние показателей гемостаза на результаты применения тромболизиса при острой сосудистой патологии

ЭА Климентова, РЕ Калинин, АС Пшенников… - Тромбоз, гемостаз и …, 2024 - thrj.ru
Одним из активно используемых методов лечения пациентов с острой сосудистой
патологией (ишемический инсульт, инфаркт миокарда, острая ишемия нижних …

Proteomic Applications and Considerations: From Research to Patient Care

N Letunica, C McCafferty, E Swaney, T Cai… - … : Methods and Protocols, 2023 - Springer
Despite technological advancements in the field of proteomics, the rate at which serum and
plasma biomarkers identified using proteomic approaches are translated into clinical use …

Variations in Blood Platelet Proteome and Transcriptome Revealed Altered Expression of Transgelin-2 in Acute Coronary Syndrome Patients

R Szelenberger, P Jóźwiak, M Kacprzak… - International Journal of …, 2022 - mdpi.com
Proteomic analyses based on mass spectrometry provide a powerful tool for the
simultaneous identification of proteins and their signatures. Disorders detection at the …