Advanced nitric oxide generating nanomedicine for therapeutic applications

Z Wang, A Jin, Z Yang, W Huang - ACS nano, 2023 - ACS Publications
Nitric oxide (NO), a gaseous transmitter extensively present in the human body, regulates
vascular relaxation, immune response, inflammation, neurotransmission, and other crucial …

[HTML][HTML] Gaseous signaling molecule-releasing hybrid nanomaterials for therapeutic applications

I Lugoloobi, Y Fang, F Jiang, G Zhang, J Hu - Giant, 2023 - Elsevier
Given their relevance in various physiological and pathophysiological mechanisms,
gaseous signaling molecules (GSMs), such as nitric oxide (NO), carbon monoxide (CO), and …

Biofilm heterogeneity-adaptive photoredox catalysis enables red light-triggered nitric oxide release for combating drug-resistant infections

J Cheng, G Gan, S Zheng, G Zhang, C Zhu… - Nature …, 2023 - nature.com
The formation of biofilms is closely associated with persistent and chronic infections, and
physiological heterogeneity such as pH and oxygen gradients renders biofilms highly …

Photocatalytic manipulation of Ca2+ signaling for regulating cellular and animal behaviors via MOF-enabled H2O2 generation

Z Zhang, Y Luo, Y Ma, Y Zhou, D Zhu, W Shen… - Science …, 2024 - science.org
The in situ generation of H2O2 in cells in response to external stimulation has exceptional
advantages in modulating intracellular Ca2+ dynamics, including high controllability and …

Visible‐Light‐Driven NO Release from Postmodified MOFs via Photoinduced Electron Transfer for Antibacterial Application

DB Hao, JL Li, XC Zhou, YY Li, ZX Zhao, R Zhou - Small, 2024 - Wiley Online Library
Photoresponsive nitric oxide (NO)‐releasing materials (NORMs) enable the spatiotemporal
delivery of NO to facilitate their potential applications in physiological conditions. Here two …

[HTML][HTML] Direct and indirect approaches to red-shift photoactivated nitric oxide release

HM Elbeheiry, M Schulz - Coordination Chemistry Reviews, 2024 - Elsevier
Nitric oxide (NO) is an important biochemical molecule that is endogenously produced to act
for instance as neurotransmitter, effect cell growth, or to regulate the immune response …

Recent advances on the development of NO-releasing molecules (NORMs) for biomedical applications

R Bhowmik, M Roy - European Journal of Medicinal Chemistry, 2024 - Elsevier
Nitric oxide (NO) is an important biological messenger as well as a signaling molecule that
participates in a broad range of physiological events and therapeutic applications in …

Photostimulated Extended Nitric Oxide (NO) Release from Water-Soluble Block Copolymer to Enhance Antibacterial Activity

S Paul, P Ashrit, M Kumar, S Mete, S Ghosh… - …, 2023 - ACS Publications
N-Nitrosamines are well established motifs to release nitric oxide (NO) under
photoirradiation. Herein, a series of amphiphilic N-nitrosamine-based block copolymers …

Induction of cervical disc degeneration and discogenic pain by low concentration Propionibacterium acnes infection: an in vivo animal study

J Li, H Li, Y Chen, D Bei, B Huang, K Gan… - Arthritis Research & …, 2024 - Springer
Background Although cervical intervertebral disc (IVD) degeneration is closely associated
with neck pain, its cause remains unclear. In this study, an animal model of cervical disc …

Therapeutic factors and biomaterial-based delivery tools for degenerative intervertebral disc repair

H Song, C Guo, Y Wu, Y Liu, Q Kong… - Frontiers in Cell and …, 2024 - frontiersin.org
Intervertebral disc degeneration (IDD) is the main cause of low back pain (LBP), which
significantly impacts global wellbeing and contributes to global productivity declines …