The maintenance of iron homeostasis is essential for proper cardiac function. A growing
body of evidence suggests that iron imbalance is the common denominator in many …

Transforming growth factor-β (TGFβ) isoforms are upregulated and activated in myocardial
diseases and have an important role in cardiac repair and remodelling, regulating the …

Sodium-glucose cotransporter 2 inhibitors (SGLT2i), a new drug class approved for
treatment of diabetes, have been shown to possess a favorable metabolic profile and to …

Diabetic cardiomyopathy (DCM) is a serious cardiac complication of diabetes that currently
lacks specific treatment. The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon …

Diabetes is a disorder of glucose metabolism, and over 90% are type 2 diabetes. Diabetic
cardiomyopathy (DCM) is one of the type 2 diabetes complications, usually accompanied by …

Diabetes is a chronic metabolic disease that is increasing in prevalence and causes many
complications. Diabetic cardiomyopathy (DCM) is a complication of diabetes that is …

The prevalence of Type 2 diabetes mellitus (T2DM) has reached pandemic proportions.
T2DM frequently causes macrovascular and/or microvascular pathologic changes and …

There is a close relationship between diabetes mellitus and heart failure, and diabetes is an
independent risk factor for heart failure. Diabetes and heart failure are linked by not only the …

Cardiovascular disease (CVD) remains the leading cause of mortality globally, so further
investigation is required to identify its underlying mechanisms and potential targets for its …

Copper is an essential trace metal element that significantly affects human physiology and
pathology by regulating various important biological processes, including mitochondrial …