Ovarian cancer has the highest mortality of all of the gynecological malignancies. There are
several distinct histotypes of this malignancy characterized by specific molecular events and …

An understanding of the molecular pathogenesis and heterogeneity of ovarian cancer holds
promise for the development of early detection strategies and novel, efficient therapies. In …

In chickens, the embryonic ovary differentiates into two distinct domains before meiosis: a
steroidogenic core (the female medulla), overlain by the germ cell niche (the cortex). The …

The laying hen (Gallus domesticus) is a robust animal model for epithelial ovarian cancer.
The use of animal models is critical in identifying early disease markers and developing and …

Simple Summary The tumor-surrounding niche comprises not only cancer cells but also
stromal cells, signaling molecules, secreted factors and the extracellular matrix. This niche …

The laying hen is the spontaneous model of ovarian tumor. A comprehensive comparison
based on RNA-seq from hens and women may shed light on the molecular mechanisms of …

Nowadays, targeted therapy plays a growing role in oncological treatment. In ovarian
cancer, particularly promising results are achieved with poly (ADP-ribose) polymerase …

Представлен систематический обзор современных методов экспериментального
изучения рака яичников, использующих традиционные (иммунокомпетентные …

Agriculture and grain production are the economical backbone of many South American
countries, with Brazil and Argentina occupying leading positions amongst worldwide …

A via de sinalização mTOR é associada à regulação da proliferação celular, e quando
desregulada, induz diversas doenças, entre elas neoplasia ovariana. Como as galinhas …