Tetraspanins compose a family of structurally related molecules with four transmembrane
domains. A total of 33 tetraspanins are present in the human genome, and tetraspanins are …

In vitro propagation studies have established that human immunodeficiency virus type 1
(HIV-1) is most efficiently transmitted at the virological synapse that forms between producer …

Tetraspanin proteins on host cells are involved in the pathogenesis of infectious diseases at
different stages. In this review, we will focus on tetraspanins expressed in the immune …

Lentiviral vectors (LVs) have provided an efficient way to integrate our gene of interest into
eukaryote cells. Human immunodeficiency virus (HIV)-derived LVs have been vastly studied …

Tetraspanins are a family of ubiquitously expressed and conserved proteins, which are
characterized by four transmembrane domains and the formation of a short and a large …

We have discovered that an N‐terminal deletion mutant of a membrane protein,
CD63,(CD63ΔN) blocks entry of CXCR4‐using, T‐cell tropic human immunodeficiency virus …

The Moloney murine leukemia virus (MMLV) belongs to the Retroviridae family of enveloped
viruses, which is known to acquire minute amounts of host cellular proteins both on the …

Highlights•Tetraspanins are small membrane proteins with major role in cell signaling.•
Tetraspanins are important actors in proliferative, immunologic and infectious pathological …

Members of the tetraspanin superfamily of proteins are implicated in a variety of complex cell
processes including cell fusion. However, the contribution of individual tetraspanins to these …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which originated in
Wuhan, the Hubei region of China, has become a pandemic worldwide. It can transmit …