Tetraspanins (TETs) function as key molecular scaffolds for surface signal recognition and
transduction via the assembly of tetraspanin-enriched microdomains. TETs' function in …

The tetraspanin CD9 has been shown to interact with different members of the β1 and β3
subfamilies of integrins, regulating through these interactions cell adhesion, migration and …

The identification of novel targets and strategies for therapy of microbial infections is an area
of intensive research due to the failure of conventional vaccines or antibiotics to combat both …

Tetraspanins are suggested to regulate the composition of cell membrane components and
control intracellular transport, which leaves them vulnerable to utilization by pathogens such …

Tetraspanins are differentially expressed in monocyte subsets and modified by inflammatory
situations including HIV-1 infection. Tetraspanins are a family of membrane-organizing …

Background Previously, we showed that the tetraspanin membrane protein CD63 mediates
both early and post-integration stages of the HIV-1 replication cycle. The temporal roles of …

The plasma membrane of immune cells is a highly organized cell structure that is key to the
initiation and regulation of innate and adaptive immune responses. It is well-established that …

Tetraspanins are small integral membrane proteins that are known to control a variety of
cellular processes, including signaling, migration and cell–cell fusion. Research over the …

The fusion of human immunodeficiency virus type 1 (HIV-1) to host cells is a dynamic
process governed by the interaction between glycoproteins on the viral envelope and the …

CD63 也被称为溶酶体相关膜蛋白3 (LAMP3), 属于四次跨膜蛋白超家族成员,
广泛表达于许多细胞类型的表面, 与细胞的活化, 黏附, 变异及肿瘤的侵袭, 转移等多种生命过程 …