Urinary tract infections (UTIs) are common, recurrent infections that can be mild to life-
threatening. The continued emergence of antibiotic resistance, together with our increasing …

Urinary tract infections (UTIs) are highly prevalent, lead to considerable patient morbidity,
incur large financial costs to health-care systems and are one of the most common reasons …

Urologists rarely need to consider bacteria beyond their role in infectious disease. However,
emerging evidence shows that the microorganisms inhabiting many sites of the body …

Key Clinical Points Acute Uncomplicated Cystitis and Pyelonephritis Acute uncomplicated
cystitis rarely progresses to severe disease, even if untreated; thus, the primary goal of …

Urinary tract infections (UTIs) are among the most common bacterial infections acquired in
the community and in hospitals. In individuals without anatomical or functional …

Introduction Pragmatic randomized controlled trials (RCTs) mimic usual clinical practice and
they are critical to inform decision-making by patients, clinicians and policy-makers in real …

Study question Can treatment of the symptoms of uncomplicated urinary tract infection (UTI)
with ibuprofen reduce the rate of antibiotic prescriptions without a significant increase in …

Objective To investigate whether symptomatic treatment with non-steroidal anti-inflammatory
drugs (NSAIDs) is non-inferior to antibiotics in the treatment of uncomplicated lower urinary …

The bladder is continuously protected by passive defences such as a mucus layer,
antimicrobial peptides and secretory immunoglobulins; however, these defences are …

Urinary tract infections (UTI) are one of the most common bacterial infections, with roughly
eleven‐million cases reported in the US each year that cost an estimated $5 billion annually …