[HTML][HTML] Pathologic classification of “pancreatic cancers”: current concepts and challenges

ME Mostafa, I Erbarut-Seven… - Chinese clinical …, 2018 - cco.amegroups.org
As the most common and most important cancer of the pancreas, with rapid mortality and
now also as the third leading cause of cancer-related deaths in the United States, pancreatic …

Pathology–grading and staging of GEP-NETs

P Capelli, M Fassan, A Scarpa - Best Practice & Research Clinical …, 2012 - Elsevier
Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) constitute a heterogeneous
group of neoplasms. In the last few decades, due to a substantial rise in incidence and …

CT radiomics may predict the grade of pancreatic neuroendocrine tumors: a multicenter study

D Gu, Y Hu, H Ding, J Wei, K Chen, H Liu, M Zeng… - European …, 2019 - Springer
Objective To develop and validate a radiomics-based nomogram for preoperatively
predicting grade 1 and grade 2/3 tumors in patients with pancreatic neuroendocrine tumors …

Cancer cells retrace a stepwise differentiation program during malignant progression

S Saghafinia, K Homicsko, A Di Domenico… - Cancer discovery, 2021 - AACR
Pancreatic neuroendocrine tumors (PanNET) comprise two molecular subtypes, relatively
benign islet tumors (IT) and invasive, metastasis-like primary (MLP) tumors. Until now, the …

Pancreatic neuroendocrine tumor: prediction of the tumor grade using magnetic resonance imaging findings and texture analysis with 3-T magnetic resonance

C Guo, S Ren, X Chen, Q Wang, W Xiao… - Cancer management …, 2019 - Taylor & Francis
Purpose The purpose of this study was to evaluate the performance of magnetic resonance
imaging (MRI) findings and texture parameters for prediction of the histopathologic grade of …

[HTML][HTML] Behavior of small, asymptomatic, nonfunctioning pancreatic neuroendocrine tumors (NF-PNETs)

JG Jung, KT Lee, YS Woo, JK Lee, KH Lee, KT Jang… - Medicine, 2015 - journals.lww.com
Small nonfunctioning pancreatic neuroendocrine tumors (NF-PNETs) usually exhibit
minimal or no growth over many years. However, there is a controversy regarding the …

Pancreatic neuroendocrine tumors: correlation between histogram analysis of apparent diffusion coefficient maps and tumor grade

JAS Pereira, E Rosado, M Bali, T Metens, SL Chao - Abdominal imaging, 2015 - Springer
Purpose To explore the role of histogram analysis of apparent diffusion coefficient (ADC)
MRI maps based on entire tumor volume data in determining pancreatic neuroendocrine …

SST gene hypermethylation acts as a pan‐cancer marker for pancreatic ductal adenocarcinoma and multiple other tumors: toward its use for blood‐based diagnosis

M Manoochehri, Y Wu, NA Giese, O Strobel… - Molecular …, 2020 - Wiley Online Library
Aberrant DNA methylation is often involved in carcinogenesis. Our initial goal was to identify
DNA methylation biomarkers associated with pancreatic cancer. A genomewide methylation …

[HTML][HTML] Metastatic pancreatic neuroendocrine tumors feature elevated T cell infiltration

J Greenberg, J Limberg, A Verma, D Kim, X Chen… - JCI insight, 2022 - ncbi.nlm.nih.gov
Pancreatic neuroendocrine tumors (PNETs) are malignancies arising from the islets of
Langerhans. Therapeutic options are limited for the over 50% of patients who present with …

Intravoxel incoherent motion diffusion-weighted imaging of pancreatic neuroendocrine tumors: prediction of the histologic grade using pure diffusion coefficient and …

EJ Hwang, JM Lee, JH Yoon, JH Kim, JK Han… - Investigative …, 2014 - journals.lww.com
Purpose The purpose of this study was to assess the value of intravoxel incoherent motion
and diffusion-weighted imaging for predicting the histologic grade of pancreatic …