The association between sarcopenia and diabetes: from pathophysiology mechanism to therapeutic strategy

H Chen, X Huang, M Dong, S Wen… - … Syndrome and Obesity, 2023 - Taylor & Francis
Diabetes and sarcopenia are emerging as serious public health issues. Sarcopenia, an age-
related disorder characterized by loss of skeletal muscle mass and function, is recognized …

Management of type 2 diabetes mellitus in elderly patients with frailty and/or sarcopenia

J Sanz-Cánovas, A López-Sampalo… - International journal of …, 2022 - mdpi.com
The life expectancy of the population is increasing worldwide due to improvements in the
prevention, diagnosis, and treatment of diseases. This favors a higher prevalence of type 2 …

DPP-4 inhibitors for treating T2DM-hype or hope? an analysis based on the current literature

K Saini, S Sharma, Y Khan - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
DPP-4 inhibition is an interesting line of therapy for treating Type 2 Diabetes Mellitus (T2DM)
and is based on promoting the incretin effect. Here, the authors have presented a brief …

Anti‐diabetic drugs and sarcopenia: emerging links, mechanistic insights, and clinical implications

X Zhang, Y Zhao, S Chen… - Journal of cachexia …, 2021 - Wiley Online Library
Sarcopenia, characterized by loss of skeletal muscle mass, quality, and strength, has
become a common hallmark of ageing and many chronic diseases. Diabetes mellitus …

Sarcopenia and type 2 diabetes: Pathophysiology and potential therapeutic lifestyle interventions

A Marcotte-Chénard, B Oliveira, JP Little… - Diabetes & Metabolic …, 2023 - Elsevier
Aims Sarcopenia generally refers to the age-related reduction in muscle strength, functional
ability, and muscle mass. Sarcopenia is a multifactorial condition associated with poor …

Skeletal muscle as a treatment target for older adults with diabetes mellitus: The importance of a multimodal intervention based on functional category

T Omura, A Araki - Geriatrics & Gerontology International, 2022 - Wiley Online Library
Although the lifespan of people with diabetes has increased in many countries, the age‐
related increase in comorbidities (sarcopenia, frailty and disabilities) and diabetic …

Sarcopenia and diabetes: A detrimental liaison of advancing age

G Lisco, OE Disoteo, A De Tullio, V De Geronimo… - Nutrients, 2023 - mdpi.com
Sarcopenia is an age-related clinical complaint characterized by the progressive
deterioration of skeletal muscle mass and strength over time. Type 2 diabetes (T2D) is …

Repurposing Drugs for Diabetes Mellitus as Potential Pharmacological Treatments for Sarcopenia–A Narrative Review

MD Witham, A Granic, E Pearson, SM Robinson… - Drugs & Aging, 2023 - Springer
Sarcopenia, the age-related loss of muscle strength and mass or quality, is a common
condition with major adverse consequences. Although the pathophysiology is incompletely …

[HTML][HTML] Type 2 diabetes mellitus and sarcopenia as comorbid chronic diseases in older adults: established and emerging treatments and therapies

J Mesinovic, JJ Fyfe, J Talevski… - … & Metabolism Journal, 2023 - ncbi.nlm.nih.gov
Type 2 diabetes mellitus (T2DM) and sarcopenia (low skeletal muscle mass and function)
share a bidirectional relationship. The prevalence of these diseases increases with age and …

Sarcopenia is associated with the Geriatric Nutritional Risk Index in elderly patients with poorly controlled type 2 diabetes mellitus

S Matsuura, K Shibazaki, R Uchida… - Journal of Diabetes …, 2022 - Wiley Online Library
ABSTRACT Aims/Introduction Diabetes and sarcopenia have a two‐way relationship with
each other with advanced age. Additionally, malnutrition is correlated with a higher risk of …