Organic synthesis using nitroxides
Nitroxides, also known as nitroxyl radicals, are long-lived or stable radicals with the general
structure R1R2N–O•. The spin distribution over the nitroxide N and O atoms contributes to …
structure R1R2N–O•. The spin distribution over the nitroxide N and O atoms contributes to …
Aerobic oxidative functionalization of indoles
S Liu, F Zhao, X Chen, GJ Deng… - Advanced Synthesis & …, 2020 - Wiley Online Library
The synthetic methodology for direct indole functionalizations is of great significance in
indole chemistry and has been intensively investigated in the last few decades. From the …
indole chemistry and has been intensively investigated in the last few decades. From the …
Visible-light-induced, graphene oxide-promoted C3-chalcogenylation of indoles strategy under transition-metal-free conditions
Q Huang, X Peng, H Li, H He, L Liu - Molecules, 2022 - mdpi.com
An efficient and general method for the synthesis of 3-sulfenylindoles and 3-selenylindoles
employing visible-light irradiation with graphene oxide as a promoter at room temperature …
employing visible-light irradiation with graphene oxide as a promoter at room temperature …
Recent studies of bifunctionalization of simple indoles
ZY Wang, S Xu, KK Wang, N Kong… - Asian Journal of Organic …, 2021 - Wiley Online Library
Indole structures are extremely important and widely employed in organic synthesis. This
review will focus on direct bifunctionalizations of simple indoles in tandem reactions. Recent …
review will focus on direct bifunctionalizations of simple indoles in tandem reactions. Recent …
Drug discovery and development for schistosomiasis
CR Caffrey, N El‐Sakkary, P Mäder… - … : drug discovery and …, 2019 - Wiley Online Library
Schistosomiasis is a neglected disease of poverty that is caused by several species of the
trematode flatworm, Schistosoma. Treatment relies on just one drug, the …
trematode flatworm, Schistosoma. Treatment relies on just one drug, the …
Graphene oxide as a green carbon material for cross-coupling of indoles with ethers via oxidation and the Friedel–Crafts reaction
X Peng, Y Zen, Q Liu, L Liu, H Wang - Organic Chemistry Frontiers, 2019 - pubs.rsc.org
Mild reaction conditions were developed to access 3, 3′-bisindolylmethane derivatives with
excellent regioselectivity at 25° C based on a new graphene oxide (GO)-promoted alkylation …
excellent regioselectivity at 25° C based on a new graphene oxide (GO)-promoted alkylation …
The direct C3 chalcogenylation of indolines using a graphene-oxide-promoted and visible-light-induced synergistic effect
C Liu, X Peng, D Hu, F Shi, P Huang, J Luo… - New Journal of …, 2020 - pubs.rsc.org
A new and efficient method for the C3–chalcogenylation of indolines, employing visible light
irradiation, and graphene oxide as a promoter, at room temperature has been achieved. The …
irradiation, and graphene oxide as a promoter, at room temperature has been achieved. The …
Regioselective synthesis of 2, 3′-biindoles mediated by an NBS-induced homo-coupling of indoles
P Huang, X Peng, D Hu, H Liao, S Tang… - Organic & Biomolecular …, 2017 - pubs.rsc.org
Mild conditions have been developed to achieve NBS-induced homodimerization of indole
derivatives with excellent regioselectivity at 15° C in high efficiency. This method provides a …
derivatives with excellent regioselectivity at 15° C in high efficiency. This method provides a …
Bioprospecting of Nitrogenous Heterocyclic Scaffolds with Potential Action for Neglected Parasitosis: A Review
SL Albino, JM da Silva, MS de C Nobre… - Current …, 2020 - ingentaconnect.com
Neglected parasitic diseases are a group of infections currently considered as a worldwide
concern. This fact can be attributed to the migration of these diseases to developed and …
concern. This fact can be attributed to the migration of these diseases to developed and …
B (C6F5) 3-catalyzed regio-and stereoselective cyanation of isatogens and their derivatives
R Sakai, N Ishihara, S Harada, S Arai - Tetrahedron Letters, 2024 - Elsevier
Herein we report the regioselective cyanation of isatogen (3-indolone N-oxide) and its
derivatives. The high electrophilicity of isatogen is a key feature for their various chemical …
derivatives. The high electrophilicity of isatogen is a key feature for their various chemical …