Mobile genetic elements associated with antimicrobial resistance
SR Partridge, SM Kwong, N Firth… - Clinical microbiology …, 2018 - Am Soc Microbiol
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …
increasing major health care problem around the world. It is now abundantly clear that both …
Transfer of antibiotic resistance in Staphylococcus aureus
Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers.
Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance …
Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance …
Evolution of plasmid mobility: origin and fate of conjugative and nonconjugative plasmids
C Coluzzi, MP Garcillán-Barcia… - Molecular Biology …, 2022 - academic.oup.com
Conjugation drives the horizontal transfer of adaptive traits across prokaryotes. One-fourth of
the plasmids encode the functions necessary to conjugate autonomously, the others being …
the plasmids encode the functions necessary to conjugate autonomously, the others being …
Origins of transfer establish networks of functional dependencies for plasmid transfer by conjugation
Plasmids can be transferred between cells by conjugation, thereby driving bacterial
evolution by horizontal gene transfer. Yet, we ignore the molecular mechanisms of transfer …
evolution by horizontal gene transfer. Yet, we ignore the molecular mechanisms of transfer …
[HTML][HTML] Bacterial chromosomal mobility via lateral transduction exceeds that of classical mobile genetic elements
S Humphrey, A Fillol-Salom, N Quiles-Puchalt… - Nature …, 2021 - nature.com
It is commonly assumed that the horizontal transfer of most bacterial chromosomal genes is
limited, in contrast to the frequent transfer observed for typical mobile genetic elements …
limited, in contrast to the frequent transfer observed for typical mobile genetic elements …
[HTML][HTML] Molecular basis of bacterial disinfectant resistance
S Mc Carlie, CE Boucher, RR Bragg - Drug Resistance Updates, 2020 - Elsevier
Antibiotic resistance could accelerate humanity towards an already fast-approaching post-
antibiotic era, where disinfectants and effective biosecurity measures will be critically …
antibiotic era, where disinfectants and effective biosecurity measures will be critically …
Prevalence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae under divergent evolutionary patterns
D Tian, X Liu, W Chen, Y Zhou, D Hu… - Emerging microbes & …, 2022 - Taylor & Francis
ABSTRACT K1/K2 hvKP strains acquire carbapenem-resistance plasmids, known as CR-
hvKp, and carbapenem-resistant Klebsiella pneumoniae (CRKP) strains obtain virulence …
hvKp, and carbapenem-resistant Klebsiella pneumoniae (CRKP) strains obtain virulence …
[HTML][HTML] Structure and evolution of Acinetobacter baumannii plasmids
AD Salgado-Camargo, S Castro-Jaimes… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii is an emergent bacterial pathogen that provokes many types of
infections in hospitals around the world. The genome of this organism consists of a …
infections in hospitals around the world. The genome of this organism consists of a …
[HTML][HTML] Staphylococcal phages and pathogenicity islands drive plasmid evolution
S Humphrey, Á San Millán, M Toll-Riera… - Nature …, 2021 - nature.com
Conjugation has classically been considered the main mechanism driving plasmid transfer
in nature. Yet bacteria frequently carry so-called non-transmissible plasmids, raising …
in nature. Yet bacteria frequently carry so-called non-transmissible plasmids, raising …
Plasmids do not consistently stabilize cooperation across bacteria but may promote broad pathogen host-range
Horizontal gene transfer via plasmids could favour cooperation in bacteria, because transfer
of a cooperative gene turns non-cooperative cheats into cooperators. This hypothesis has …
of a cooperative gene turns non-cooperative cheats into cooperators. This hypothesis has …