Mobile genetic elements associated with antimicrobial resistance

SR Partridge, SM Kwong, N Firth… - Clinical microbiology …, 2018 - Am Soc Microbiol
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

Transfer of antibiotic resistance in Staphylococcus aureus

J Haaber, JR Penadés, H Ingmer - Trends in microbiology, 2017 - cell.com
Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers.
Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance …

Evolution of plasmid mobility: origin and fate of conjugative and nonconjugative plasmids

C Coluzzi, MP Garcillán-Barcia… - Molecular Biology …, 2022 - academic.oup.com
Conjugation drives the horizontal transfer of adaptive traits across prokaryotes. One-fourth of
the plasmids encode the functions necessary to conjugate autonomously, the others being …

Origins of transfer establish networks of functional dependencies for plasmid transfer by conjugation

M Ares-Arroyo, C Coluzzi, EPC Rocha - Nucleic Acids Research, 2023 - academic.oup.com
Plasmids can be transferred between cells by conjugation, thereby driving bacterial
evolution by horizontal gene transfer. Yet, we ignore the molecular mechanisms of transfer …

[HTML][HTML] Bacterial chromosomal mobility via lateral transduction exceeds that of classical mobile genetic elements

S Humphrey, A Fillol-Salom, N Quiles-Puchalt… - Nature …, 2021 - nature.com
It is commonly assumed that the horizontal transfer of most bacterial chromosomal genes is
limited, in contrast to the frequent transfer observed for typical mobile genetic elements …

[HTML][HTML] Molecular basis of bacterial disinfectant resistance

S Mc Carlie, CE Boucher, RR Bragg - Drug Resistance Updates, 2020 - Elsevier
Antibiotic resistance could accelerate humanity towards an already fast-approaching post-
antibiotic era, where disinfectants and effective biosecurity measures will be critically …

Prevalence of hypervirulent and carbapenem-resistant Klebsiella pneumoniae under divergent evolutionary patterns

D Tian, X Liu, W Chen, Y Zhou, D Hu… - Emerging microbes & …, 2022 - Taylor & Francis
ABSTRACT K1/K2 hvKP strains acquire carbapenem-resistance plasmids, known as CR-
hvKp, and carbapenem-resistant Klebsiella pneumoniae (CRKP) strains obtain virulence …

[HTML][HTML] Structure and evolution of Acinetobacter baumannii plasmids

AD Salgado-Camargo, S Castro-Jaimes… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii is an emergent bacterial pathogen that provokes many types of
infections in hospitals around the world. The genome of this organism consists of a …

[HTML][HTML] Staphylococcal phages and pathogenicity islands drive plasmid evolution

S Humphrey, Á San Millán, M Toll-Riera… - Nature …, 2021 - nature.com
Conjugation has classically been considered the main mechanism driving plasmid transfer
in nature. Yet bacteria frequently carry so-called non-transmissible plasmids, raising …

Plasmids do not consistently stabilize cooperation across bacteria but may promote broad pathogen host-range

AE Dewar, JL Thomas, TW Scott, G Wild… - Nature ecology & …, 2021 - nature.com
Horizontal gene transfer via plasmids could favour cooperation in bacteria, because transfer
of a cooperative gene turns non-cooperative cheats into cooperators. This hypothesis has …