[HTML][HTML] The landscape of immune therapy in vulnerable patients with advanced non-small cell lung cancer: a narrative review

K Morimoto, T Yamada, K Takayama - Translational Lung Cancer …, 2023 - ncbi.nlm.nih.gov
Methods Herein, we defined vulnerable as the group of patients with NSCLC and
performance status (PS)≥ 2 (poor PS), advanced age (≥ 75 years), or cancer cachexia. We …

Why does malaise/fatigue occur? Underlying mechanisms and potential relevance to treatments in rheumatoid arthritis

Y Tanaka, K Ikeda, Y Kaneko, N Ishiguro… - Expert Review of …, 2024 - Taylor & Francis
Introduction Fatigue and malaise are commonly associated with a wide range of medical
conditions, including rheumatoid arthritis (RA). Evidence suggests that fatigue and malaise …

[HTML][HTML] Metabolism study of anamorelin, a GHSR1a receptor agonist potentially misused in sport, with human hepatocytes and LC-HRMS/MS

PS Gameli, O Taoussi, G Basile, J Carlier, FP Busardò - Metabolites, 2023 - mdpi.com
Anamorelin, developed for the treatment of cancer cachexia, is an orally active medication
that improves appetite and food intake, thereby increasing body mass and physical …

[HTML][HTML] Cachexia and Sarcopenia in Oligometastatic Non-Small Cell Lung Cancer: Making a Potential Curable Disease Incurable?

V Bartolomeo, M Jongbloed, WRPH van de Worp… - Cancers, 2024 - mdpi.com
Simple Summary Synchronous oligometastatic non-small cell lung cancer (NSCLC)
represents an intermediate state of metastatic disease with a limited number of metastases …

Cancer cachexia as a predictor of adverse outcomes in patients with non-small cell lung cancer: A meta-analysis

J Zhang, X Tang, W Zhang, Y Xu, H Zhang, Y Fan - Clinical Nutrition, 2024 - Elsevier
Introduction Cancer cachexia is a complex problem characterized by weight loss due to
skeletal muscle and adipose tissue reduction. The purpose of this meta-analysis is to …

Similar Efficacy Observed for First-Line Immunotherapy in Racial/Ethnic Minority Patients With Metastatic NSCLC

M Lee, J Liu, E Miao, S Wang, F Zhang, J Wei… - Journal of the National …, 2023 - jnccn.org
Background: Limited data exist on the impact of immunotherapy use in ethnic minority
patients with non–small cell lung cancer (NSCLC), because they have been …

[HTML][HTML] Cancer Cachexia: New Insights and Future Directions

CR Mariean, OM Tiucă, A Mariean, OS Cotoi - Cancers, 2023 - mdpi.com
Simple Summary Cancer is a major burden of disease worldwide, with cancer cachexia
being a poor prognosis factor which leads to a decreased quality of life and overall survival …

[HTML][HTML] Real world prognostic utility of platelet lymphocyte ratio and nutritional status in first-line immunotherapy response in stage IV non-small cell lung cancer

M MacDonald, D Poei, A Leyba, R Diep… - Cancer Treatment and …, 2023 - Elsevier
Background Elevated platelet lymphocyte ratio (PLR) and low body mass index (BMI) are
associated with inferior survival in non-small cell lung cancer (NSCLC) patients receiving …

[HTML][HTML] The Prognostic Value of the Novel Global Immune-Nutrition-Inflammation Index (GINI) in Stage IIIC Non-Small Cell Lung Cancer Patients Treated with …

E Topkan, U Selek, B Pehlivan, A Kucuk, D Ozturk… - Cancers, 2023 - mdpi.com
Simple Summary We investigated the prognostic significance of the newly created Global
Immune-Nutrition-Inflammation Index (GINI) in IIIC non-small cell lung cancer (NSCLC) …

[HTML][HTML] Development and Characterization of a Cancer Cachexia Rat Model Transplanted with Cells of the Rat Lung Adenocarcinoma Cell Line Sato Lung Cancer …

E Kasumi, M Chiba, Y Kuzumaki, H Kuzuoka, N Sato… - Biomedicines, 2023 - mdpi.com
Cancer cachexia is a complex malnutrition syndrome that causes progressive dysfunction.
This syndrome is accompanied by protein and energy losses caused by reduced nutrient …