[HTML][HTML] An adipocentric perspective on the development and progression of non-alcoholic fatty liver disease
E Lee, H Korf, A Vidal-Puig - Journal of hepatology, 2023 - Elsevier
Alongside the liver, white adipose tissue (WAT) is critical in regulating systemic energy
homeostasis. Although each organ has its specialised functions, they must work …
homeostasis. Although each organ has its specialised functions, they must work …
The role of GDF15 as a myomitokine
Growth differentiation factor 15 (GDF15) is a cytokine best known for affecting systemic
energy metabolism through its anorectic action. GDF15 expression and secretion from …
energy metabolism through its anorectic action. GDF15 expression and secretion from …
Stress-induced FGF21 and GDF15 in obesity and obesity resistance
Fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (GDF15) are
established as stress-responsive cytokines that can modulate energy balance by increasing …
established as stress-responsive cytokines that can modulate energy balance by increasing …
The adipocyte supersystem of insulin and cAMP signaling
A Guilherme, LA Rowland, H Wang, MP Czech - Trends in cell biology, 2023 - cell.com
Adipose tissue signals to brain, liver, and muscles to control whole body metabolism through
secreted lipid and protein factors as well as neurotransmission, but the mechanisms …
secreted lipid and protein factors as well as neurotransmission, but the mechanisms …
Exercise-mediated browning of white adipose tissue: its significance, mechanism and effectiveness
WJ Mu, JY Zhu, M Chen, L Guo - International Journal of Molecular …, 2021 - mdpi.com
As a metabolic organ, adipose tissue plays an important role in regulating metabolism. In
adults, most adipose tissue is white adipose tissue (WAT), and excessive expansion of WAT …
adults, most adipose tissue is white adipose tissue (WAT), and excessive expansion of WAT …
New developments in the biology of fibroblast growth factors
DM Ornitz, N Itoh - WIREs mechanisms of disease, 2022 - Wiley Online Library
The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+ T cells
C Hu, W Qiao, X Li, Z Ning, J Liu, S Dalangood, H Li… - Cell metabolism, 2024 - cell.com
Tumors employ diverse strategies for immune evasion. Unraveling the mechanisms by
which tumors suppress anti-tumor immunity facilitates the development of immunotherapies …
which tumors suppress anti-tumor immunity facilitates the development of immunotherapies …
Cytokines and exosomal miRNAs in skeletal muscle–adipose crosstalk
L Guo, M Quan, W Pang, Y Yin, F Li - Trends in Endocrinology & …, 2023 - cell.com
Skeletal muscle and adipose tissues (ATs) are secretory organs that release secretory
factors including cytokines and exosomes. These factors mediate muscle–adipose crosstalk …
factors including cytokines and exosomes. These factors mediate muscle–adipose crosstalk …
Deficiency of adipose aryl hydrocarbon receptor protects against diet-induced metabolic dysfunction through sexually dimorphic mechanisms
The molecular mechanisms underlying diet-induced obesity are complex and remain
unclear. The activation of the aryl hydrocarbon receptor (AhR), a xenobiotic sensor, by …
unclear. The activation of the aryl hydrocarbon receptor (AhR), a xenobiotic sensor, by …
The nuanced metabolic functions of endogenous FGF21 depend on the nature of the stimulus, tissue source, and experimental model
RA Spann, CD Morrison, LJ den Hartigh - Frontiers in endocrinology, 2022 - frontiersin.org
Fibroblast growth factor 21 (FGF21) is a hormone that is involved in the regulation of lipid,
glucose, and energy metabolism. Pharmacological FGF21 administration promotes weight …
glucose, and energy metabolism. Pharmacological FGF21 administration promotes weight …