Efficacy and toxicity of a paediatric protocol in teenagers and young adults with Philadelphia chromosome negative acute lymphoblastic leukaemia: results from …
R Hough, C Rowntree, N Goulden… - British journal of …, 2016 - Wiley Online Library
Despite the substantial outcome improvements achieved in paediatric acute lymphoblastic
leukaemia (ALL), survival in teenage and young adult (TYA) patients has remained inferior …
leukaemia (ALL), survival in teenage and young adult (TYA) patients has remained inferior …
Outcomes of acute lymphoblastic leukemia with KMT2A (MLL) rearrangement: the MD Anderson experience
G Richard-Carpentier, HM Kantarjian, G Tang… - Blood …, 2021 - ashpublications.org
Acute lymphoblastic leukemia (ALL) with t (4; 11)(q21; q23)-KMT2A-AFF1 is associated with
a poor prognosis. The impact of KMT2A rearrangements other than t (4; 11) is uncertain, and …
a poor prognosis. The impact of KMT2A rearrangements other than t (4; 11) is uncertain, and …
Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia
H Ueno, K Yoshida, Y Shiozawa, Y Nannya… - Blood …, 2020 - ashpublications.org
Recent genetic studies using high-throughput sequencing have disclosed genetic
alterations in B-cell precursor acute lymphoblastic leukemia (B-ALL). However, their effects …
alterations in B-cell precursor acute lymphoblastic leukemia (B-ALL). However, their effects …
Prognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia
S Krentz, J Hof, A Mendioroz, R Vaggopoulou, P Dörge… - Leukemia, 2013 - nature.com
Despite risk-adapted treatment, survival of children with relapse of acute lymphoblastic
leukemia (ALL) remains poor compared with that of patients with initial diagnosis of ALL …
leukemia (ALL) remains poor compared with that of patients with initial diagnosis of ALL …
Validation of the United Kingdom copy-number alteration classifier in 3239 children with B-cell precursor ALL
Genetic abnormalities provide vital diagnostic and prognostic information in pediatric acute
lymphoblastic leukemia (ALL) and are increasingly used to assign patients to risk groups …
lymphoblastic leukemia (ALL) and are increasingly used to assign patients to risk groups …
Use of minimal residual disease assessment to redefine induction failure in pediatric acute lymphoblastic leukemia
D O'Connor, AV Moorman, R Wade… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Our aim was to determine the role of end-of-induction (EOI) minimal residual
disease (MRD) assessment in the identification and stratification of induction failure in …
disease (MRD) assessment in the identification and stratification of induction failure in …
The origin of b-cells: Human fetal b cell development and implications for the pathogenesis of childhood acute lymphoblastic leukemia
TR Jackson, RE Ling, A Roy - Frontiers in immunology, 2021 - frontiersin.org
Human B-lymphopoiesis is a dynamic life-long process that starts in utero by around six post-
conception weeks. A detailed understanding of human fetal B-lymphopoiesis and how it …
conception weeks. A detailed understanding of human fetal B-lymphopoiesis and how it …
Acute lymphoblastic leukemia
CJ Harrison, B Johansson - … Cytogenetics: Chromosomal and …, 2015 - Wiley Online Library
Acute lymphoblastic leukemia (ALL) is classified as B‐lineage ALL (B‐ALL) and T‐lineage
ALL (T‐ALL). The incidence of ALL is almost three times higher in white than black children …
ALL (T‐ALL). The incidence of ALL is almost three times higher in white than black children …
Detection of prognostically relevant genetic abnormalities in childhood B‐cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and …
Treatment of childhood acute lymphoblastic leukaemia (ALL) has improved considerably in
recent years. A contributing factor has been the improved stratification for treatment …
recent years. A contributing factor has been the improved stratification for treatment …
Clinical features, early treatment responses, and outcomes of pediatric acute lymphoblastic leukemia in China with or without specific fusion transcripts: a single …
C Gao, XX Zhao, WJ Li, L Cui, W Zhao… - American journal of …, 2012 - Wiley Online Library
Acute lymphoblastic leukemia (ALL) with distinct fusion transcripts has unique clinical
features. In this study, the incidence, clinical characteristics, early treatment response, and …
features. In this study, the incidence, clinical characteristics, early treatment response, and …