Acute lymphoblastic leukemia (ALL) is the most common childhood cancer; however, its
genetic diversity limits investigation into the molecular pathogenesis of disease and …

A disease risk index (DRI) that was developed for adults with hematologic malignancy who
were undergoing hematopoietic cell transplantation is also being used to stratify children …

The event-free survival (EFS) for pediatric acute lymphoblastic leukemia (ALL) has shown
remarkable improvement in the past several decades. In Korea also, a recent study showed …

The fusion gene MLL/AF4 defines a high-risk subtype of pro-B acute lymphoblastic
leukemia. Relapse can be associated with a lineage switch from acute lymphoblastic to …

Simple Summary The latest molecular taxonomy of acute lymphoblastic leukemia (ALL)
comprises> 20 distinct genetic subtypes, each with their own unique clinical and prognostic …

The IKZF 1 gene at 7p12. 2 codes for IKAROS (also termed IKZF 1), an essential
transcription factor in haematopoiesis involved primarily in lymphoid differentiation. Its …

PURPOSE The aim of the randomized trial, UKALL2003, was to adjust treatment intensity on
the basis of minimal residual disease (MRD) stratification for children and young adults with …

B-lymphoblastic leukemia/lymphoma, also known as B-acute lymphoblastic leukemia, is
derived from B-cell progenitors. B-acute lymphoblastic leukemia occurs predominantly in …

The biology and outcome of adult t (4; 11)(q21; q23)/MLL-AFF1 acute lymphoblastic
leukemia are poorly understood. We describe the outcome and delineate prognostic factors …

Genetic profiling is important for disease evaluation and prediction of prognosis or
responsiveness to therapy in neoplasia. Microarray technologies, including array …