Harnessing human microbiomes for disease prediction
The human microbiome has been increasingly recognized as having potential use for
disease prediction. Predicting the risk, progression, and severity of diseases holds promise …
disease prediction. Predicting the risk, progression, and severity of diseases holds promise …
[HTML][HTML] The correlation between gut microbiome and atrial fibrillation: pathophysiology and therapeutic perspectives
N Li, L Wang, L Li, MZ Yang, QX Wang, XW Bai… - Military Medical …, 2023 - Springer
Regulation of gut microbiota and its impact on human health is the theme of intensive
research. The incidence and prevalence of atrial fibrillation (AF) are continuously escalating …
research. The incidence and prevalence of atrial fibrillation (AF) are continuously escalating …
[HTML][HTML] Roles of gut microbiota in atrial fibrillation: insights from Mendelian randomization analysis and genetic data from over 430,000 cohort study participants
Background Gut microbiota imbalances have been suggested as a contributing factor to
atrial fibrillation (AF), but the causal relationship is not fully understood. Objectives To …
atrial fibrillation (AF), but the causal relationship is not fully understood. Objectives To …
[HTML][HTML] Integration of polygenic and gut metagenomic risk prediction for common diseases
Multiomics has shown promise in noninvasive risk profiling and early detection of various
common diseases. In the present study, in a prospective population-based cohort with~ 18 …
common diseases. In the present study, in a prospective population-based cohort with~ 18 …
[HTML][HTML] ENPP2 inhibitor improves proliferation in AOM/DSS-induced colorectal cancer mice via remodeling the gut barrier function and gut microbiota composition
J Yan, W Duan, Q Gao, T Mao, M Wang, J Duan… - Pharmacological …, 2023 - Elsevier
In our previous multicenter study, we delineated the inherent metabolic features of colorectal
cancer (CRC). Therein, we identified a member of the ectonucleotide pyrophosphatase …
cancer (CRC). Therein, we identified a member of the ectonucleotide pyrophosphatase …
[HTML][HTML] Gut microbiota, blood metabolites, and left ventricular diastolic dysfunction in US Hispanics/Latinos
Background Left ventricular diastolic dysfunction (LVDD) is an important precursor of heart
failure (HF), but little is known about its relationship with gut dysbiosis and microbial-related …
failure (HF), but little is known about its relationship with gut dysbiosis and microbial-related …
Mapping multi-omics characteristics related to short-term PM2. 5 trajectory and their impact on type 2 diabetes in middle-aged and elderly adults in Southern China
J Wang, W Hu, Z Xue, X Cai, S Zhang, F Li, L Lin… - Journal of Hazardous …, 2024 - Elsevier
The relationship between PM 2.5 and metabolic diseases, including type 2 diabetes (T2D),
has become increasingly prominent, but the molecular mechanism needs to be further …
has become increasingly prominent, but the molecular mechanism needs to be further …
[HTML][HTML] The relationship between atrial fibrillation and NLRP3 inflammasome: a gut microbiota perspective
Y Xing, L Yan, X Li, Z Xu, X Wu, H Gao, Y Chen… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) is a common clinical arrhythmia whose pathogenesis has not been fully
elucidated, and the inflammatory response plays an important role in the development of AF …
elucidated, and the inflammatory response plays an important role in the development of AF …
The dual role of 20 (S)-protopanaxadiol in alleviating pulmonary fibrosis through the gut-lung axis
Y Ruan, G Ren, M Wang, W Lv, K Shimizu, C Zhang - Phytomedicine, 2024 - Elsevier
Abstract Background Pulmonary Fibrosis (PF) is a progressive lung disease characterized
by the diffuse interstitial tissue, leading to severe breathing difficulties. The existing treatment …
by the diffuse interstitial tissue, leading to severe breathing difficulties. The existing treatment …
The Mediterranean Diet, Its Microbiome Connections, and Cardiovascular Health: A Narrative Review
V Abrignani, A Salvo, G Pacinella… - International Journal of …, 2024 - mdpi.com
The Mediterranean diet (MD), rich in minimally processed plant foods and in
monounsaturated fats but low in saturated fats, meat, and dairy products, represents one of …
monounsaturated fats but low in saturated fats, meat, and dairy products, represents one of …