The vascular endothelium is an interface between the blood stream and the vessel wall.
Changes in this single cell layer of the artery wall are believed of primary importance in the …

Atherosclerosis is a chronic progressive inflammatory process that can eventually lead to
cardiovascular disease (CVD). Despite available treatment, the prevalence of …

P2X7 receptors are ATP‐gated cation channels; their activation in macrophage also leads to
rapid opening of a membrane pore permeable to dyes such as ethidium, and to release of …

Coronary vasomotion abnormalities play important roles in the pathogenesis of ischaemic
heart disease, in which endothelial dysfunction and coronary artery spasm are substantially …

Direct intercellular communication via gap junctions is critical in the control and coordination
of vascular function. In the cardiovascular system, gap junctions are made up of one or more …

Gap junctions (GJ) and hemichannels (HC) formed from the protein subunits called
connexins are transmembrane conduits for the exchange of small molecules and ions …

The three subtypes of calcium‐activated potassium channels (KCa) of large, intermediate
and small conductance (BKCa, IKCa and SKCa) are present in the vascular wall. In healthy …

The cerebrovascular endothelium exerts a profound influence on cerebral vessels and
cerebral blood flow. This review summarizes current knowledge of various dilator and …

In the presence of aldosterone, plasma sodium in the high physiological range stiffens
endothelial cells and reduces the release of nitric oxide. We now demonstrate effects of …

Since the detection of nitric oxide two and a half decades ago, there has been an incredible
boost in endothelial function research, which is fascinating the research community …