Gliotoxin is a kind of epipolythiodioxopiperazine derived from different fungi that is
characterized by a disulfide bridge. Gliotoxins can be biosynthesized by a gli gene cluster …

Lung cancer is one of the most common and lethal cancers in human beings. Lung cancer
has been divided into two major types: small cell lung cancer (SCLC) and non-small cell …

Purpose: Co-delivery of drugs to achieve the synergistic anticancer effect is a promising
strategy for lung cancer therapy. The purpose of this research is to develop a doxorubicin …

By the end of the year 2020, there are nine marine-derived anticancer drugs available on
the market, and the field is currently growing exponentially. This process is stipulated by …

In cancer management, drug resistance remains a challenge that reduces the effectiveness
of chemotherapy. Several studies have shown that curcumin resensitizes cancer cells to …

Death-associated protein kinase 1 (DAPK1) expression induced by diverse death stimuli
mediates apoptotic activity in various cancers, including ovarian cancer. In addition, mutual …

Gliotoxin (GT) and fumagillin (FUM) are mycotoxins most abundantly produced by
Aspergillus fumigatus during the early stages of infection to cause invasive aspergillosis (IA) …

Background: Gliotoxin, a secondary metabolite isolated from marine-derived Aspergillus
fumigatus, has demonstrated anti-tumor properties in several cancers. Ferroptosis, a …

Abstract Background/Aim: Few studies have examined the correlation between pyruvate
kinase M2 (PKM2) overexpression and triple-negative breast cancer (TNBC). TNBC is …

The inadequate vascularization seen in fast-growing solid tumors gives rise to hypoxic
areas, fostering specific changes in gene expression that bolster tumor cell survival and …