Synthesis, anticancer activity and molecular docking of new quinolines, quinazolines and 1, 2, 4-triazoles with pyrido [2, 3-d] pyrimidines

AA Abu-Hashem, O Hakami, N Amri - Heliyon, 2024 - cell.com
Recently, heterocyclic compounds such as pyrido [2, 3-d] pyrimidinones, 1, 2, 4-
triazolopyrimidines, pyrimidoquinazolines, and quinoline derivatives have gained attention …

Synthesis, antimicrobial and antioxidant activities of some new pyrazolo[1,5-a]pyrimidine and imidazo[1,2-b]pyrazole derivatives based isoxazole

ZM Alamshany, NY Tashkandi… - Synthetic …, 2023 - Taylor & Francis
A new set of pyrazolo [1, 5-a] pyrimidines 5–8 and imidazo [1, 2-b] pyrazoles 9–11
incorporating isoxazole as pharmacologically attractive cores were synthesized starting with …

Facile synthesis and in vitro anticancer evaluation of a new series of tetrahydroquinoline

U Fathy, HA Abd El Salam, EA Fayed, AM Elgamal… - Heliyon, 2021 - cell.com
Tetrahydroquinoline (THQ) is an important structure for synthesizing multiple biologically
active derivatives. Thus, we developed new quinoline derivatives and investigated them as …

Recent Advances on Pyrazole-Pyrimidine/Fused Pyrimidine Hybrids with Anticancer Potential (A Review)

S Wang, S Qian, S Wang, Y Zou - Russian Journal of General Chemistry, 2023 - Springer
Cancer, caused by the failure of the mechanism that controls cell growth and proliferation, is
usually associated with severe health issues. Nowadays, chemotherapy still occupies an …

[HTML][HTML] Synthesis and evaluation of antibacterial activity of novel 3-methyl-1H-indazole derivatives

F Shaikh, M Arif, M Khushtar, M Nematullah… - Intelligent …, 2024 - Elsevier
Aim of the study was designed to synthesize and evaluate antibacterial activity of novel
heterocyclic compounds, 3-methyl-1H-indazole derivatives. The heterocyclic compounds, 3 …

Design, Synthesis, and biological evaluation of a novel series of thiazole derivatives based on pyrazoline as anticancer agents

U Fathy, MNM Yousif… - Egyptian Journal of …, 2022 - ejchem.journals.ekb.eg
This study deals with the design and synthesis of new pyrazoline-thiazole scaffold as
promising anti-cancer agents, with the goal of building new compounds with combinations of …

Imidazo-and pyrazolopyrimidine scaffolds as anticancer agents

GS Rady, MA El Deeb, M Sarg, AT Shalaby… - … International Journal of …, 2024 - journals.ekb.eg
Cancer is a global serious life threatening disease; it exerts massive impacts on diseased
human body, and causes high rate of mortality in different parts of the world. It arises from …

Design, Synthesis and Anticancer Activity of New Quinolines, Quinazolines and 1, 2, 4-Triazoles with Pyrido [2, 3-d] Pyrimidines

AA Abu-Hashem, O Hakami, N Amri - Quinazolines and - papers.ssrn.com
Design, Synthesis and Anticancer Activity of New Quinolines, Quinazolines and 1,2,4-Triazoles
with Pyrido[2,3-d] Pyrimidines by Ameen Ali Abu-Hashem, Othman Hakami, Nasser Amri …