Objective To systematically review and meta-analyse conversion rates from normal
cognition to Mild Cognitive Impairment (MCI) and dementia in Parkinson's disease (PD) …

Parkinson's disease (PD) is a common, disabling, neurodegenerative disorder. In addition to
classical motor symptoms, non-motor features are now widely accepted as part of the clinical …

Objective: Nonmotor symptoms (NMS) are common in patients with established Parkinson
disease (PD) but their frequency in early PD has not been extensively studied. Our aim was …

Objective: Using resting-state (RS) fMRI, we investigated the functional integrity of the
default-mode network (DMN) in cognitively unimpaired patients with Parkinson disease …

Cognitive impairment is common in PD, even in early stages. The construct of mild cognitive
impairment has been used to identify clinically evident cognitive impairment without …

Background Parkinson's disease (PD) is characterized by both motor and cognitive deficits.
In PD, physical exercise has been found to improve physical functioning. Recent studies …

Parkinson's disease is associated with multiple cognitive impairments and increased risk of
dementia, but the extent of these deficits varies widely among patients. The ICICLE-PD study …

Orthostatic hypotension and cognitive impairment are common in Parkinson's disease (PD)
and significantly impair quality of life. Orthostatic hypotension and cognitive impairment …

Adenosine and adenosine receptors (ARs) are increasingly recognized as important
therapeutic targets for controlling cognition under normal and disease conditions for its dual …

Cognitive impairment is one of the most salient non-motor symptoms of Parkinson disease
(PD) that poses a significant burden on the patients and carers as well as being a risk factor …