[HTML][HTML] Applications and limitations of dendrimers in biomedicine

AA Chis, C Dobrea, C Morgovan, AM Arseniu, LL Rus… - Molecules, 2020 - mdpi.com
Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …

[HTML][HTML] Dendrimers as nanocarriers for nucleic acid and drug delivery in cancer therapy

L Palmerston Mendes, J Pan, VP Torchilin - Molecules, 2017 - mdpi.com
Dendrimers are highly branched polymers with easily modifiable surfaces. This makes them
promising structures for functionalization and also for conjugation with drugs and DNA/RNA …

[HTML][HTML] Dendrimers as pharmaceutical excipients: synthesis, properties, toxicity and biomedical applications

A Santos, F Veiga, A Figueiras - Materials, 2019 - mdpi.com
The European Medicines Agency (EMA) and the Current Good Manufacturing Practices
(cGMP) in the United States of America, define excipient as the constituents of the …

[HTML][HTML] Antimicrobial photodynamic therapy: Latest developments with a focus on combinatory strategies

R Youf, M Müller, A Balasini, F Thétiot, M Müller… - Pharmaceutics, 2021 - mdpi.com
Antimicrobial photodynamic therapy (aPDT) has become a fundamental tool in modern
therapeutics, notably due to the expanding versatility of photosensitizers (PSs) and the …

Progress in microalgal mediated bioremediation systems for the removal of antibiotics and pharmaceuticals from wastewater

N Chandel, V Ahuja, R Gurav, V Kumar… - Science of the Total …, 2022 - Elsevier
Worldwide demand for antibiotics and pharmaceutical products is continuously increasing
for the control of disease and improvement of human health. Poor management and partial …

[HTML][HTML] Nanoparticles in the diagnosis and treatment of vascular aging and related diseases

H Xu, S Li, YS Liu - Signal Transduction and Targeted Therapy, 2022 - nature.com
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

[HTML][HTML] Advancement in solubilization approaches: a step towards bioavailability enhancement of poorly soluble drugs

L Kumari, Y Choudhari, P Patel, GD Gupta, D Singh… - Life, 2023 - mdpi.com
A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …

Dendrimers as nanoscale vectors: Unlocking the bars of cancer therapy

AD Dey, A Bigham, Y Esmaeili, M Ashrafizadeh… - Seminars in Cancer …, 2022 - Elsevier
Chemotherapy is the first choice in the treatment of cancer and is always preferred to other
approaches such as radiation and surgery, but it has never met the need of patients for a …

[HTML][HTML] PAMAM dendrimer-cell membrane interactions

LJ Fox, RM Richardson, WH Briscoe - Advances in colloid and interface …, 2018 - Elsevier
PAMAM dendrimers have been conjectured for a wide range of biomedical applications due
to their tuneable physicochemical properties. However, their application has been hindered …

[HTML][HTML] Nano strategies for berberine delivery, a natural alkaloid of Berberis

E Mirhadi, M Rezaee, B Malaekeh-Nikouei - Biomedicine & …, 2018 - Elsevier
Berberine, as a phytochemical component of some medicinal Chinese herbs (most
frequently Berberis vulgaris), is an isoquinoline alkaloid with many therapeutic effects …