Lipoprotein receptor signalling in atherosclerosis

C Mineo - Cardiovascular research, 2020 - academic.oup.com
The founding member of the lipoprotein receptor family, low-density lipoprotein receptor
(LDLR) plays a major role in the atherogenesis through the receptor-mediated endocytosis …

[HTML][HTML] Functional roles of sphingolipids in immunity and their implication in disease

M Lee, SY Lee, YS Bae - Experimental & molecular medicine, 2023 - nature.com
Sphingolipids, which are components of cellular membranes and organ tissues, can be
synthesized or degraded to modulate cellular responses according to environmental cues …

Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis

C Ding, R Shrestha, X Zhu, AE Geller, S Wu… - Nature …, 2023 - nature.com
Metastasis is the leading cause of cancer-related deaths and myeloid cells are critical in the
metastatic microenvironment. Here, we explore the implications of reprogramming pre …

Sphingolipid metabolism during Toll‐like receptor 4 (TLR4)‐mediated macrophage activation

A Olona, C Hateley, S Muralidharan… - British journal of …, 2021 - Wiley Online Library
Macrophage activation in response to stimulation of Toll‐like receptor 4 (TLR4) provides a
paradigm for investigating energy metabolism that regulates the inflammatory response …

Immunoengineering strategies to enhance vascularization and tissue regeneration

J Zarubova, MM Hasani-Sadrabadi, R Ardehali… - Advanced drug delivery …, 2022 - Elsevier
Immune cells have emerged as powerful regulators of regenerative as well as pathological
processes. The vast majority of regenerative immunoengineering efforts have focused on …

[HTML][HTML] Link between serum lipid signature and prognostic factors in COVID-19 patients

M Dei Cas, S Ottolenghi, C Morano, R Rinaldo… - Scientific Reports, 2021 - nature.com
Although the serum lipidome is markedly affected by COVID-19, two unresolved issues
remain: how the severity of the disease affects the level and the composition of serum lipids …

[HTML][HTML] Alterations of lipid metabolism provide serologic biomarkers for the detection of asymptomatic versus symptomatic COVID-19 patients

AH Janneh, MF Kassir, CJ Dwyer, P Chakraborty… - Scientific reports, 2021 - nature.com
COVID-19 pandemic exerts a health care emergency around the world. The illness severity
is heterogeneous. It is mostly unknown why some individuals who are positive for SARS …

[HTML][HTML] Macrophages play a key role in tissue repair and regeneration

Y Yu, Z Yue, M Xu, M Zhang, X Shen, Z Ma, J Li, X Xie - PeerJ, 2022 - peerj.com
Tissue regeneration after body injury has always been a complex problem to resolve for
mammals. In adult mammals, the repair process after tissue injury is often accompanied by …

Fatty acid elongation by ELOVL6 hampers remyelination by promoting inflammatory foam cell formation during demyelination

AV Garcia Corrales, SGS Verberk… - Proceedings of the …, 2023 - National Acad Sciences
A hallmark of multiple sclerosis (MS) is the formation of multiple focal demyelinating lesions
within the central nervous system (CNS). These lesions mainly consist of phagocytes that …

[HTML][HTML] A digital health platform for assisting the diagnosis and monitoring of COVID-19 progression: An adjuvant approach for augmenting the antiviral response and …

Y Ishay, A Potruch, A Schwartz, M Berg, K Jamil… - Biomedicine & …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), which is a respiratory illness associated
with high mortality, has been classified as a pandemic. The major obstacles for the clinicians …