Abstract IL-6, IL-17, IL-23 and IL-1β are the crucial cytokines controlling inflammatory and
immune response during L. major infection. During cutaneous leishmaniasis, an important T …

Endometriosis is a common condition in women of reproductive age, but its current
interventions are unsatisfactory. Recent research discovered a dysregulation of the …

Frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) is a complex
heterogeneous neurodegenerative disorder for which mechanisms are poorly understood …

The tumor microenvironment comprises both tumor and non-tumor stromal cells, including
tumor-associated macrophages (TAMs), endothelial cells, and carcinoma-associated …

Recent studies suggested an important contribution of sphingosine-1-phospate (S1P)
signaling via its specific receptors (S1PRs) in the production of pro-inflammatory mediators …

Psoriasis is considered a systemic disease associated with metabolic abnormalities, and it is
important to understand the mechanisms by which metabolism affects pathophysiological …

Sphingolipids are key molecules in inflammation and defense against pathogens. Their role
in dectin-1/TLR2-mediated responses is, however, poorly understood. This study …

Intraplaque hemorrhage (IPH) accelerates atherosclerosis progression. To scavenge
excessive red blood cells (RBCs), vascular smooth muscle cells (VSMCs) with great …

Acute inflammation resolution acts as a vital process for active host response, tissue support,
and homeostasis maintenance, during which resolvin D (RvD) and E (RvE) as mediators …

Lipids are complex organic compounds made up of carbon, oxygen, and hydrogen. These
play a diverse and intricate role in cellular processes like membrane trafficking, protein …