Growing bodies of evidence have demonstrated that the identification of prostate cancer
(PCa) biomarkers in the patients' blood and urine may remarkably improve PCa diagnosis …

Circulating tumor cells (CTCs) detach from primary or metastatic lesions and circulate in the
peripheral blood, which is considered to be the cause of distant metastases. CTC analysis in …

Stem and progenitor cells of the adult prostate epithelium have historically been believed to
reside mainly or exclusively within the basal cell compartment and to possess basal-like …

In advanced prostate cancer, access to recent diagnostic tissue samples is restricted and
this affects the analysis of the association of evolving biomarkers such as AR-V7 with …

Simple Summary Cell-dependent and cell-independent information drawn from the blood
stream were merged into the attractive term “liquid biopsy” and tentatively applied to most …

Background Prostate-specific antigen (PSA) is used for diagnosing prostate cancer, but
does not reflect the characteristics of prostate cancer cells to allow assessment of cancer …

Response to androgen receptor signaling inhibitors (ARSI) varies widely in metastatic
castration resistant prostate cancer (mCRPC). To improve treatment guidance, biomarkers …

Secreted proteins (SPs) play important roles in diverse important biological processes;
however, a comprehensive and high-quality list of human SPs is still lacking. Here we …

Although there are molecularly distinct subtypes of prostate cancer, no molecular
classification system is used clinically. The ribonucleotide reductase small subunit M2 …

New classification systems based on molecular features have been introduced to improve
precision medicine for prostate cancer (PCa). This review covers the increasing risk of PCa …