Glycosyltransferases catalyse the transfer of a glycosyl moiety from a donor to an acceptor.
Members of this enzyme class are ubiquitous throughout all kingdoms of life and are …

C-glycosides represent a large group of natural products with a CC bond between the
aglycone and the sugar moiety. They exhibit great structural diversity, wide natural …

Biological degradation of natural product glycosides involves, alongside hydrolysis, β-
elimination for glycosidic bond cleavage. Here, we discover an O-glycoside β-eliminase …

Covering: up to 2021 Terpenoids are physiologically active substances that are of great
importance to humans. Their physicochemical properties are modified by glycosylation, in …

Glycosylation is a successful strategy to alter the pharmacological properties of small
molecules, and it has emerged as a unique approach to expand the chemical space of …

Covering: up to 2020 C-Glycosyltransferases are enzymes that catalyse the transfer of sugar
molecules to carbon atoms in substituted aromatic rings of a variety of natural products. The …

Cascade reactions have been described as efficient and universal tools, and are of
substantial interest in synthetic organic chemistry. This review article provides an overview …

Uridine diphosphate-dependent glycosyltransferases (UGTs) in plants catalyze O-, C-, S-
and N-glycosylation of diverse substrates to yield a wide variety of glycosides with broad …

Small-molecule glycosides that exhibit a β-d-ribosyl residue linked to an aglycone via a
noncanonical C-glycosidic linkage are of great biological importance. They occur naturally …

Highlights•Glycoside hydrolases can be converted into proficient transglycosidases.•It is
possible to switch the bond-type specificity of O/C/N/S-glycosyltransferases.•Glycoside …