Novel Mannich bases derived from 1, 2, 4-triazoles: Design, synthesis, characterization, and glutathione S-transferase inhibition properties investigations

O Akyıldırım, H Medetalibeyoğlu, E Oğuz, A Aras… - Journal of Molecular …, 2023 - Elsevier
The reaction of variously substituted 1, 2, 4-triazole derivatives with morpholine and
formaldehyde represents an efficient and easy-to-set synthetic entry toward heterocyclic N …

Synthesis and acetylcholinesterase enzyme inhibitory effects of some novel 4,5-Dihydro-1H-1,2,4-triazol-5-one derivatives; an in vitro and in silico study

H Medetalibeyoğlu, F Türkan, S Manap… - Journal of …, 2023 - Taylor & Francis
In this study, a series of novel Schiff bases (4a-4h) containing 1, 2, 4-triazole structure were
synthesized through a condensation reaction of 3-alkyl (aryl)-4-amino-4, 5-dihydro-1 H-1, 2 …

Decomposition of triazole and 3-nitrotriazole upon low-energy electron attachment

M Saqib, F Izadi, LU Isierhienrhien, M Ončák… - Physical Chemistry …, 2023 - pubs.rsc.org
Compounds based on nitrotriazole have been studied for their application as potential
radiosensitizers for the treatment of tumors and as energetic materials. In the former …

[PDF][PDF] Synthesis of 1, 2, 4 triazole compounds

H MEDETALİBEYOĞLU, G KOTAN - 2022 - isres.org
As highly privileged heterocyclic scaffolds, 1, 2, 4-triazoles have many uses in the fields of
biology, pharmacology, and materials science (Gulyaev et al., 2021; Brandt et al., 2007; Cai …