Interactions between the microbiota, immune and nervous systems in health and disease

TC Fung, CA Olson, EY Hsiao - Nature neuroscience, 2017 - nature.com
The diverse collection of microorganisms that inhabit the gastrointestinal tract, collectively
called the gut microbiota, profoundly influences many aspects of host physiology, including …

Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms

A Inserra, D De Gregorio, G Gobbi - Pharmacological Reviews, 2021 - ASPET
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …

Mortality risk among patients with COVID-19 prescribed selective serotonin reuptake inhibitor antidepressants

T Oskotsky, I Marić, A Tang, B Oskotsky… - JAMA network …, 2021 - jamanetwork.com
Importance Antidepressant use may be associated with reduced levels of several
proinflammatory cytokines suggested to be involved with the development of severe COVID …

[HTML][HTML] Critical neurotransmitters in the neuroimmune network

TW Hodo, MTP De Aquino, A Shimamoto… - Frontiers in …, 2020 - frontiersin.org
Immune cells rely on cell-cell communication to specify and fine-tune their responses. They
express an extensive network of cell communication modes, including a vast repertoire of …

5-Hydroxytryptamine (serotonin) in the gastrointestinal tract

MD Gershon - Current opinion in endocrinology, diabetes and …, 2013 - journals.lww.com
5-Hydroxytryptamine (serotonin) in the gastrointestinal trac... : Current Opinion in
Endocrinology, Diabetes and Obesity 5-Hydroxytryptamine (serotonin) in the …

The role of serotonin and its receptors in activation of immune responses and inflammation

MS Shajib, WI Khan - Acta physiologica, 2015 - Wiley Online Library
Abstract Serotonin or 5‐hydroxytryptamine (5‐HT) is a neurotransmitter and hormone that
contributes to the regulation of various physiological functions by its actions in the central …

Neuropharmacology of N, N-dimethyltryptamine

TM Carbonaro, MB Gatch - Brain research bulletin, 2016 - Elsevier
Abstract N, N-dimethyltryptamine (DMT) is an indole alkaloid widely found in plants and
animals. It is best known for producing brief and intense psychedelic effects when ingested …

[HTML][HTML] Serotonin—Its synthesis and roles in the healthy and the critically ill

M Kanova, P Kohout - International journal of molecular sciences, 2021 - mdpi.com
Serotonin (5-hydroxytryptamine, 5-HT) plays two important roles in humans—one central
and the other peripheral—depending on the location of the 5-HT pools of on either side of …

A dialogue between the immune system and brain, spoken in the language of serotonin

NL Baganz, RD Blakely - ACS chemical neuroscience, 2013 - ACS Publications
Neuropsychiatric disorders have long been linked to both immune system activation and
alterations in serotonin (5-HT) signaling. In the CNS, the contributions of 5-HT modulate a …

[HTML][HTML] Tryptophan‐derived serotonin‐kynurenine balance in immune activation and intestinal inflammation

S Haq, JA Grondin, WI Khan - The FASEB Journal, 2021 - ncbi.nlm.nih.gov
Endogenous tryptophan metabolism pathways lead to the production of serotonin (5‐
hydroxytryptamine; 5‐HT), kynurenine, and several downstream metabolites which are …