Objective: To review the evidence regarding antiepileptic drug (AED) prophylaxis in patients
with severe traumatic brain injury (TBI) in order to make practice recommendations …

Posttraumatic epilepsy is a major source of disability following traumatic brain injury (TBI)
and a common cause of medically-intractable epilepsy. Previous attempts to prevent the …

Epilepsy comprises a group of disorders characterized by the periodic occurrence of
seizures, and pathologic specimens from patients with temporal lobe epilepsy demonstrate …

Epilepsy, affecting about 1% of the population, comprises a group of disorders of the brain
characterized by the periodic and unpredictable occurrence of seizures. Epilepsy is a major …

Purpose: Traumatic brain injury has long been known to be a cause of epilepsy. Most
information on risk factors for developing posttraumatic seizures is from before computed …

Traumatic Brain Injury Rehabilitation: State of the Science : American Journal of Physical
Medicine & Rehabilitation Traumatic Brain Injury Rehabilitation: State of the Science : American …

Background Head injury is a common event and can cause a spectrum of motor and
cognition disabilities. A frequent complication is seizures. Antiepileptic drugs (AED) such as …

Dikmen SS, Bombardier CH, Machamer JE, Fann JR, Temkin NR. Natural history of
depression in traumatic brain injury. Arch Phys Med Rehabil 2004; 85: 1457–64 …

Background Traumatic brain injury (TBI) initiates a complex series of neurochemical and
signaling changes that lead to pathological events including neuronal hyperactivity …

Most current treatments for epilepsy are symptomatic therapies that suppress seizures but
do not affect the underlying course or prognosis of epilepsy. The need for disease‐modifying …