Episodic memory proves essential for daily function, allowing us to remember where we
parked the car, what time we walked the dog, or what a friend said earlier. In" How We …

A growing body of evidence indicates that neuronal nicotinic acetylcholine receptors
(nAChRs), in addition to promoting fast cholinergic transmission, may modulate other …

The α7 nicotinic acetylcholine receptor (nAChR) plays an important role in cognitive
processes and may represent a drug target for treating cognitive deficits in …

Cholinergic innervation of the hippocampus uses the neurotransmitter acetylcholine (ACh)
to coordinate neuronal circuit activity while simultaneously influencing the function of non …

Alteration by β-amyloid (Aβ) of signaling via nicotinic acetylcholine receptors (nAChRs) has
been implicated in the early stages of Alzheimer's disease. nAChRs function both post-and …

Addictive drugs can activate systems involved in normal reward-related learning, creating
long-lasting memories of the drug's reinforcing effects and the environmental cues …

Acetylcholine (ACh) is an important neurotransmitter of the CNS that binds both nicotinic and
muscarinic receptors to exert its action. However, the mechanisms underlying the effects of …

To elucidate the neural correlates of cognitive effects of nicotine, we examined behavioral
performance and blood oxygenation level-dependent regional brain activity, using functional …

Desensitization is an intriguing characteristic of ligand-gated channels, whereby a decrease
or loss of biological response occurs following prolonged or repetitive stimulation. Nicotinic …

Rationale Nicotine affects many aspects of human cognition, including attention and
memory. Activation of nicotinic acetylcholine receptors (nAChRs) in neuronal networks …