The role of nicotinic acetylcholine receptors in the mechanisms of anesthesia

E Tassonyi, E Charpantier, D Muller, L Dumont… - Brain research …, 2002 - Elsevier
Nicotinic acetylcholine receptors are members of the ligand-gated ion channel superfamily,
that includes also gamma-amino-butiric-acidA, glycine, and 5-hydroxytryptamine3 receptors …

The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system

MD Santos, M Alkondon, EFR Pereira, Y Aracava… - Molecular …, 2002 - ASPET
In this study, the patch-clamp technique was used to determine the effects of galantamine, a
cholinesterase inhibitor and a nicotinic allosteric potentiating ligand (APL) used for treatment …

Function of local circuits in the hippocampal dentate gyrus-CA3 system

Y Senzai - Neuroscience Research, 2019 - Elsevier
Anatomical observations, theoretical work and lesioning experiments have supported the
idea that the CA3 in the hippocampus is important for encoding, storage and retrieval of …

Cholinergic modulation of hippocampal cells and circuits

SR Cobb, CH Davies - The Journal of physiology, 2005 - Wiley Online Library
Septohippocampal cholinergic fibres ramify extensively throughout the hippocampal
formation to release acetylcholine upon a diverse range of muscarinic and nicotinic …

Nicotinic acetylcholine receptors in sensory cortex

R Metherate - Learning & Memory, 2004 - learnmem.cshlp.org
Acetylcholine release in sensory neocortex contributes to higher-order sensory function, in
part by activating nicotinic acetylcholine receptors (nAChRs). Molecular studies have …

Nicotinic modulation of human auditory sensory memory: evidence from mismatch negativity potentials

T Baldeweg, D Wong, KE Stephan - International Journal of …, 2006 - Elsevier
Impairment in mismatch negativity (MMN) generation is a robust biological marker of
schizophrenia. Understanding the physiological and pharmacological processes involved in …

Neuro-transmitters in the central nervous system & their implication in learning and memory processes

HJ Reis, C Guatimosim, M Paquet… - Current medicinal …, 2009 - ingentaconnect.com
This review article gives an overview of a number of central neuro-transmitters, which are
essential for integrating many functions in the central nervous system (CNS), such as …

RgIA4 potently blocks mouse α9α10 nAChRs and provides long lasting protection against oxaliplatin-induced cold allodynia

SB Christensen, AJ Hone, I Roux, J Kniazeff… - Frontiers in cellular …, 2017 - frontiersin.org
Transcripts for α9 and α10 nicotinic acetylcholine receptor (nAChR) subunits are found in
diverse tissues. The function of α9α10 nAChRs is best known in mechanosensory cochlear …

Cellular, molecular, and genetic substrates underlying the impact of nicotine on learning

TJ Gould, PT Leach - Neurobiology of learning and memory, 2014 - Elsevier
Addiction is a chronic disorder marked by long-lasting maladaptive changes in behavior and
in reward system function. However, the factors that contribute to the behavioral and …

5-Hydroxyindole potentiates human α7 nicotinic receptor-mediated responses and enhances acetylcholine-induced glutamate release in cerebellar slices

R Zwart, G De Filippi, LM Broad, GI McPhie… - …, 2002 - Elsevier
The effects of 5-hydroxyindole (5-HI) have been investigated on human α7 nicotinic
acetylcholine receptors (nAChRs) expressed in Xenopus oocytes and GH4 cells, on native …