Clues to the Design of Aggregation-Resistant Insulin from Proline Scanning of Highly Amyloidogenic Peptides Derived from the N-Terminal Segment of the A-Chain

W Puławski, R Dec, W Dzwolak - Molecular Pharmaceutics, 2024 - ACS Publications
Insulin aggregation poses a significant problem in pharmacology and medicine as it occurs
during prolonged storage of the hormone and in vivo at insulin injection sites. We have …

Insights into the mechanism of peptide fibril growth on gold surface

S Mondal, T Karmakar - Biophysical Chemistry, 2024 - Elsevier
Understanding the formation of β-fibrils over the gold surface is of paramount interest in
nano-bio-medicinal Chemistry. The intricate mechanism of self-assembly of …