Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease

G De Rubis, KR Paudel, L Corrie, S Mehndiratta… - Naunyn-Schmiedeberg's …, 2023 - Springer
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …

Unravelling the in vivo dynamics of liposomes: Insights into biodistribution and cellular membrane interactions

S Paramshetti, M Angolkar, S Talath, RAM Osmani… - Life Sciences, 2024 - Elsevier
Liposomes, as a colloidal drug delivery system dating back to the 1960s, remain a focal
point of extensive research and stand as a highly efficient drug delivery method. The …

Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug Delivery

A Al-Jipouri, À Eritja, M Bozic - International Journal of Molecular …, 2023 - mdpi.com
Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …

Field-flow fractionation-an excellent tool for fractionation, isolation and/or purification of biomacromolecules

SK Wiedmer, ML Riekkola - Journal of Chromatography A, 2023 - Elsevier
Field-flow fractionation (FFF) with its several variants, has developed into a mature
methodology. The scope of the FFF investigations has expanded, covering both a wide …

Donepezil-Loaded Nanocarriers for the Treatment of Alzheimer's Disease: Superior Efficacy of Extracellular Vesicles Over Polymeric Nanoparticles

R Oliveira Silva, H Counil, JM Rabanel… - International Journal …, 2024 - Taylor & Francis
Introduction Drug delivery across the blood-brain barrier (BBB) is challenging and therefore
severely restricts neurodegenerative diseases therapy such as Alzheimer's disease (AD) …

[HTML][HTML] Piperlongumine inhibits proliferation and oncogenic MYCN expression in chemoresistant metastatic retinoblastoma cells directly and through extracellular …

C Shi, K Huang, J Soto, R Sankaran, V Kalia… - Biomedicine & …, 2023 - Elsevier
Ocular retinoblastoma malignancies, which develop into metastatic phenotypes, result in
poor prognosis and survival for infant and child patients. To improve the prognosis of …

Pulmonary drug delivery devices and nanosystems as potential treatment strategies for acute respiratory distress syndrome (ARDS)

CT Dhege, P Kumar, YE Choonara - International Journal of Pharmaceutics, 2024 - Elsevier
Despite advances in drug delivery technologies, treating acute respiratory distress
syndrome (ARDS) is challenging due to pathophysiological barriers such as lung injury …

[HTML][HTML] Pulmonary inhalation for disease treatment: Basic research and clinical translations

B Wang, L Wang, Q Yang, Y Zhang, T Qinglai, X Yang… - Materials Today Bio, 2024 - Elsevier
Pulmonary drug delivery has the advantages of being rapid, efficient, and well-targeted, with
few systemic side effects. In addition, it is non-invasive and has good patient compliance …

ExoDS: a versatile exosome-based drug delivery platform to target cancer cells and cancer stem cells

S Paul, S Bhagat, L Dash, HD Mohapatra… - … in Bioengineering and …, 2024 - frontiersin.org
Chemotherapy drugs like doxorubicin (Dox) are widely used in middle-income countries
around the world to treat various types of cancers, including breast cancer. Although they …

Extracellular Vesicles as Delivery Systems in Disease Therapy

MA Picon, L Wang, A Da Fonseca Ferreira… - International Journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs)/exosomes are nanosized membrane-bound structures that are
released by virtually all cells. EVs have attracted great attention in the scientific community …