ATP-sensitive potassium channel opener, Nicorandil, inhibits NF-κB/AIM2/GSDMD pathway activation to protect against neuroinflammation in ischemic stroke.

C Zhao, X Fu, Z Yang, Q Zhang… - Neurochemistry …, 2024 - Elsevier
Abstract The Absent in Melanoma 2 (AIM2) inflammasome contributes to ischemic brain
injury by inducing cell pyroptosis and inflammatory responses. Our research group has …

[HTML][HTML] Investigating the attenuating effects of metformin-loaded selenium nanoparticles coupled with Myrtus communis L. flower extract on CaOx deposition in male …

J Kang, Y Tong - Regenerative Therapy, 2024 - Elsevier
Kidney stones are a foremost clinical concern in urology with CaOx crystals accounting for
roughly 80% of these renal formations. This research endeavor seeks to ascertain the …