Understanding cellular interactions with nanomaterials: Towards a rational design of medical nanodevices

F Villanueva-Flores, A Castro-Lugo, OT Ramírez… - …, 2020 - iopscience.iop.org
Biomedical applications increasingly require fully characterized new nanomaterials. There is
strong evidence showing that nanomaterials not only interact with cells passively but also …

Extracellular vesicles: Emerging anti-cancer drugs and advanced functionalization platforms for cancer therapy

M Wu, M Wang, H Jia, P Wu - Drug Delivery, 2022 - Taylor & Francis
Increasing evidences show that unmodified extracellular vesicles (EVs) derived from various
cells can effectively inhibit the malignant progression of different types of tumors by …

The effect of shape on cellular uptake of gold nanoparticles in the forms of stars, rods, and triangles

X Xie, J Liao, X Shao, Q Li, Y Lin - Scientific reports, 2017 - nature.com
Gold nanomaterials have attracted considerable interest as vehicles for intracellular drug
delivery. In our study, we synthesized three different shapes of methylpolyethylene glycol …

Repeated-oral dose toxicity of polyethylene microplastics and the possible implications on reproduction and development of the next generation

EJ Park, JS Han, EJ Park, E Seong, GH Lee, DW Kim… - Toxicology letters, 2020 - Elsevier
With the increased distribution of microplastics in the environment, the potential for harmful
effects on human health and ecosystems have become a global concern. Considering that …

Chromatin reprogramming and bone regeneration in vitro and in vivo via the microtopography-induced constriction of cell nuclei

X Wang, V Agrawal, CL Dunton, Y Liu… - Nature biomedical …, 2023 - nature.com
Topographical cues on cells can, through contact guidance, alter cellular plasticity and
accelerate the regeneration of cultured tissue. Here we show how changes in the nuclear …

Materials and design approaches for a fully bioresorbable, electrically conductive and mechanically compliant cardiac patch technology

H Ryu, X Wang, Z Xie, J Kim, Y Liu, W Bai… - Advanced …, 2023 - Wiley Online Library
Myocardial infarction (MI) is one of the leading causes of death and disability. Recently
developed cardiac patches provide mechanical support and additional conductive paths to …

Quantifying the level of nanoparticle uptake in mammalian cells using flow cytometry

HR Shin, M Kwak, TG Lee, JY Lee - Nanoscale, 2020 - pubs.rsc.org
Reliable quantification of nanoparticle uptake in mammalian cells is essential to study the
effects of nanoparticles in the fields of medicine and environmental science. Most …

The effects of surface functionality and size of gold nanoparticles on neuronal toxicity, apoptosis, ROS production and cellular/suborgan biodistribution

I Ozcicek, N Aysit, C Cakici, A Aydeger - Materials Science and …, 2021 - Elsevier
Gold nanoparticles are emerging as promising nanomaterials to create nanoscale
therapeutic delivery systems. The aim of the study was to synthesis of highly monodisperse …

Insight into the interactions between nanoparticles and cells

J Li, H Mao, N Kawazoe, G Chen - Biomaterials science, 2017 - pubs.rsc.org
Multifunctional nanoparticles (NPs) have been widely used in biomedical applications
because of their versatile properties. The properties of NPs should be well designed and …

Polymer decorated gold nanoparticles in nanomedicine conjugates

I Capek - Advances in colloid and interface science, 2017 - Elsevier
Noble metal, especially gold nanoparticles and their conjugates with biopolymers have
immense potential for disease diagnosis and therapy on account of their surface plasmon …