Super-enhancers (SEs) are cell-specific DNA cis-regulatory elements that can supervise the
transcriptional regulation processes of downstream genes. SEdb 2.0 (http://www. licpathway …

In light of a global rise in the number of patients with type 2 diabetes mellitus (T2DM) and
obesity, non-alcoholic fatty liver disease (NAFLD), now known as metabolic dysfunction …

The genus Ruta in the family Rutaceae includes about 40 species, such as the well-known
plants R. graveolens L.(common rue) or R. chalepensis L.(fringed rue), but also much lesser …

The present study investigated the anti-tumour effects of scoparone, also known as 6, 7-
dimethoxycoumarin, in non-small-cell-lung cancer (NSCLC) cells. It was discovered that …

Background Glioma, a type of malignant brain tumor, has become a challenging health
issue globally in recent years. Methods In this study, we investigated the potential …

Scoparone (SCO) is a compound found in the stems and leaves of Artemisia capillaris. The
pharmacological uses of SCO include significant hypotensive, cholagogic, anti …

Colorectal cancer (CRC) is one of most common malignancies worldwide, yet curative
therapy remains a clinical challenge. Here, we demonstrate that scoparone (Scop), a …

Breast cancer is a frequently occurring malignant tumor that is one of the leading causes of
cancer-related deaths in women worldwide. Monoclonal antibodies that block programed …

Abstract Background Anaplastic Thyroid Carcinoma (ATC) is a rare and deadly malignant
tumor in humans. It is prone to developing resistance to radiotherapy and chemotherapy …

The gastrointestinal tract can be affected by a number of diseases that pancreatic cancer
(PC) is a malignant manifestation of them. The prognosis of PC patients is unfavorable and …