Regenerative repair of the brain after traumatic brain injury (TBI) remains an extensive
clinical challenge, inspiring intensified interest in therapeutic approaches to explore superior …

Central nervous system (CNS) diseases are the leading cause of death worldwide. By
performing compensatory functions and improving the inflammatory microenvironment, the …

Circular RNAs (circRNAs) are a class of covalently closed single-stranded RNAs that are
expressed during the development of specific cells and tissues. CircRNAs play crucial roles …

Multidrug resistance–associated protein 4 (MRP4), a member of the C subfamily of ATP-
binding cassette transporters, is highly expressed in the kidneys of mammals and is …

Non-coding RNAs (ncRNAs), including miRNAs, lncRNAs, circRNAs, and piRNAs, do not
encode proteins. Nonetheless, they have critical roles in a variety of cellular activities—such …

Extracellular vesicles (EVs) have been increasingly recognized as essential players in cell
communication in many organs and systems, including the central nervous system (CNS). A …

Extracellular vesicles (EVs) are vital for cell-to-cell communication, transferring proteins,
lipids, and nucleic acids in various physiological and pathological processes. They play …

Nanomedicine is a newer, promising approach to promote neuroprotection,
neuroregeneration, and modulation of the blood–brain barrier. This review includes the …

环状RNAs 是一类共价闭合单链RNA 分子, 具有细胞/组织/发育特异性表达等特征. 环状RNAs
通过吸附microRNAs, 调节基因转录, 控制某些RNA 结合蛋白的活性, 以及产生功能肽等机制在 …

新生儿缺氧缺血性脑病(hypoxic-ischemic encephalopathy, HIE) 是新生儿死亡及儿童伤残的
主要原因之一. 尽管亚低温治疗已成为常规手段, 但目前治疗HIE 的方法有限且效果不理想. 此外 …