[HTML][HTML] Assessing cell migration in hydrogels: An overview of relevant materials and methods

AA Solbu, D Caballero, S Damigos, SC Kundu… - Materials Today Bio, 2023 - Elsevier
Cell migration is essential in numerous living processes, including embryonic development,
wound healing, immune responses, and cancer metastasis. From individual cells to …

Unraveling the Link between Olfactory Deficits and Neuropsychiatric Disorders

K Yang, C Ayala-Grosso, JP Bhattarai… - Journal of …, 2023 - Soc Neuroscience
Smell loss has caught public attention during the recent COVID-19 pandemic. Research on
olfactory function in health and disease gains new momentum. Smell deficits have long …

Analysis of gene expression variance in schizophrenia using structural equation modeling

AA Igolkina, C Armoskus, JRB Newman… - Frontiers in Molecular …, 2018 - frontiersin.org
Schizophrenia (SCZ) is a psychiatric disorder of unknown etiology. There is evidence
suggesting that aberrations in neurodevelopment are a significant attribute of schizophrenia …

Directional persistence of cell migration in schizophrenia patient-derived olfactory cells

JY Tee, A Mackay-Sim - International Journal of Molecular Sciences, 2021 - mdpi.com
Cell migration is critical for brain development and linked to several neurodevelopmental
disorders, including schizophrenia. We have shown previously that cell migration is …

RNA-seq analysis of gene expression profiles in posttraumatic stress disorder, Parkinson's disease and schizophrenia identifies roles for common and distinct …

SMJ Hemmings, P Swart, JS Womersely… - Discover Mental …, 2022 - Springer
Evidence suggests that shared pathophysiological mechanisms in neuropsychiatric
disorders (NPDs) may contribute to risk and resilience. We used single-gene and network …

Olfactory neuroepithelium cells from cannabis users display alterations to the cytoskeleton and to markers of adhesion, proliferation and apoptosis

A Delgado-Sequera, M Hidalgo-Figueroa… - Molecular …, 2021 - Springer
Cannabis is the third most commonly used psychoactive substance of abuse, yet it also
receives considerable attention as a potential therapeutic drug. Therefore, it is essential to …

Altered gene regulation as a candidate mechanism by which ciliopathy gene SDCCAG8 contributes to schizophrenia and cognitive function

M Flynn, L Whitton, G Donohoe… - Human Molecular …, 2020 - academic.oup.com
Mutations in genes that encode centrosomal/ciliary proteins cause severe cognitive deficits,
while common single-nucleotide polymorphisms in these genes are associated with …

A cross-species systems genetics analysis links APBB1IP as a candidate for schizophrenia and prepulse inhibition

DG Ashbrook, S Cahill, R Hager - Frontiers in behavioral …, 2019 - frontiersin.org
Background: Prepulse inhibition (PPI) of the startle response is a highly conserved form of
sensorimotor gating, disruption of which is found in schizophrenia patients and their …

Network-based prediction of polygenic disease genes involved in cell motility

M Bern, A King, DA Applewhite, A Ritz - Proceedings of the 2018 ACM …, 2018 - dl.acm.org
Schizophrenia and autism are examples of polygenic diseases caused by a multitude of
genetic variants. Recently, both diseases have been associated with disrupted neuron …

Transcriptomic and epigenomic consequences of heterozygous loss of function mutations in AKAP11, the first large-effect shared risk gene for bipolar disorder and …

N Farhangdoost, C Liao, Y Liu, M Alda, PA Dion… - bioRxiv, 2024 - biorxiv.org
The gene A-kinase anchoring protein 11 (AKAP11) recently emerged as a shared risk factor
between bipolar disorder and schizophrenia, driven by large-effect loss-of-function (LoF) …