Defining the role of natural killer cells in COVID-19

MJ Lee, CA Blish - Nature immunology, 2023 - nature.com
Natural killer (NK) cells are critical effectors of antiviral immunity. Researchers have
therefore sought to characterize the NK cell response to coronavirus disease 2019 (COVID …

[PDF][PDF] Harnessing B cell responses for personalized approaches in HIV Management

EI Obeagu, GU Obeagu - Elite Journal of Immunology, 2024 - researchgate.net
This comprehensive review explores the forefront of HIV management through the lens of
personalized medicine, with a specific focus on harnessing B cell responses. The dynamic …

[HTML][HTML] Natural killer cells in SARS-CoV-2 infection: pathophysiology and therapeutic implications

C Di Vito, F Calcaterra, N Coianiz, S Terzoli… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …

Hepatic natural killer cells: organ-specific sentinels of liver immune homeostasis and physiopathology

J Mikulak, E Bruni, F Oriolo, C Di Vito… - Frontiers in …, 2019 - frontiersin.org
The liver is considered a preferential tissue for NK cells residency. In humans, almost 50% of
all intrahepatic lymphocytes are NK cells that are strongly imprinted in a liver-specific …

On the way to become a natural killer cell

C Di Vito, J Mikulak, D Mavilio - Frontiers in immunology, 2019 - frontiersin.org
Natural Killer (NK) cells are innate lymphocytes playing pivotal roles in host defense and
immune-surveillance. The homeostatic modulation of germ-line encoded/non-rearranged …

Associations between HIV and severe mpox in an Atlanta cohort

B Aldred, JY Scott, A Aldredge… - The Journal of …, 2024 - academic.oup.com
Abstract Background In the Southeastern United States, the 2022 mpox outbreak
disproportionately impacted people who are black and people with HIV (PWH). Methods We …

The use of toll-like receptor agonists in HIV-1 cure strategies

JT Martinsen, JD Gunst, JF Højen, M Tolstrup… - Frontiers in …, 2020 - frontiersin.org
Toll-like receptors (TLRs) are a family of pattern recognition receptors and part of the first
line of defense against invading microbes. In humans, we know of 10 different TLRs, which …

Mpox and HIV—Collision of Two Diseases

J Zucker, A Hazra, BK Titanji - Current HIV/AIDS Reports, 2023 - Springer
Abstract Purpose of Review The global outbreak of mpox has brought renewed attention to a
previously neglected disease which is particularly severe in people with underlying …

Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2

AJ French, S Natesampillai, A Krogman… - PLoS …, 2020 - journals.plos.org
Eradication of HIV-1 by the “kick and kill” strategy requires reactivation of latent virus to
cause death of infected cells by either HIV-induced or immune-mediated apoptosis. To date …

Expression of the inhibitory receptor TIGIT is up-regulated specifically on NK cells with CD226 activating receptor from HIV-infected individuals

X Yin, T Liu, Z Wang, M Ma, J Lei, Z Zhang… - Frontiers in …, 2018 - frontiersin.org
Natural killer (NK) cells are important for maintenance of innate immune system stability and
serve as a first line of defense against tumors and virus infections; they can act either directly …