Background The low cost of 16S rRNA gene sequencing facilitates population-scale
molecular epidemiological studies. Existing computational algorithms can resolve 16S rRNA …

Pulmonary symptoms in cystic fibrosis (CF) begin in early life with chronic lung infections
and concomitant airway inflammation leading to progressive loss of lung function. Gradual …

Members of the archaeal Miscellaneous Crenarchaeotic Group (MCG) are among the most
successful microorganisms on the planet. During its evolutionary diversification, this very …

The majority of chronic infections are associated with mono-or polymicrobial biofilms, having
a significant impact on the patients' quality of life and survival rates. Although the use of …

Current therapy for cystic fibrosis (CF) focuses on minimizing the microbial community and
the host's immune response through the aggressive use of airway clearance techniques …

Increasingly the development of novel therapeutic strategies is taking into consideration the
contribution of the intestinal microbiota to health and disease. Dysbiosis of the microbial …

Over the last decade, technological advances have revolutionised efforts to understand the
role played by microbes in airways disease. With the application of ever more sophisticated …

Despite over a decade of cystic fibrosis (CF) microbiome research, much remains to be
learned about the overall composition, metabolic activities, and pathogenicity of the …

Persistence of microorganisms or reinfections are the main reasons for failure of root canal
therapy. Very few studies to date have included culture-independent methods to assess the …

Chronic Pseudomonas aeruginosa infections play an important role in the progress of lung
disease in patients suffering from cystic fibrosis (CF). Recent studies indicate that …