Nature and frequency of genetic disease

BR Korf, RE Pyeritz, WW Grody - … and Rimoin's Principles and Practice of …, 2019 - Elsevier
Genetic variation is a major source of phenotypic variation, the engine of evolution, and an
important cause of human pathology. Genetic variation exists along a continuum, from …

Replicated umbilical cord blood DNA methylation loci associated with gestational age at birth

TP York, SJ Latendresse, C Jackson-Cook… - Epigenetics, 2020 - Taylor & Francis
ABSTRACT DNA methylation is highly sensitive to in utero perturbations and has an
established role in both embryonic development and regulation of gene expression. The …

Gasdermin D: in vivo evidence of pyroptosis in spontaneous labor at term

N Gomez-Lopez, R Romero, B Panaitescu… - The Journal of …, 2021 - Taylor & Francis
Objective: Pyroptosis is an inflammatory form of programmed cell death that is mediated by
the activation of the inflammasome and depends on the pore-forming function of gasdermin …

Term cesarean delivery in the first pregnancy is not associated with an increased risk for preterm delivery in the subsequent pregnancy

SA Vahanian, MK Hoffman, CV Ananth, DJ Croft… - American journal of …, 2019 - Elsevier
Background Prior studies have reported an increased risk for preterm delivery following a
term cesarean delivery. However, these studies did not adjust for high-risk conditions related …

Большие акушерские синдромы:«гордиев узел» генных сетей

ВВ Ковалев, ЕВ Кудрявцева, НМ Миляева… - … журнал. 2018. Т. 168 …, 2018 - elib.usma.ru
В статье рассматриваются современные взгляды на возможную роль различных
генетических сетей в патогенезе больших акушерских синдромов. Рассмотрены гены …

Causes of preterm birth: Genetic factors in preterm birth and preterm infant phenotypes

S Dauengauer‐Kirlienė, I Domarkienė… - Journal of Obstetrics …, 2023 - Wiley Online Library
Aim The aim is to provide an overview of recent research on genetic factors that influence
preterm birth in the context of neonatal phenotypic assessment. Methods This is a …

Can we predict preterm delivery based on the previous pregnancy?

T Wainstock, R Sergienko, E Sheiner - Journal of Clinical Medicine, 2021 - mdpi.com
(1) Background: Preterm deliveries (PTD,< 37 gestational weeks) which occur in 5–18% of
deliveries across the world, are associated with immediate and long-term offspring …

[图书][B] Statistical methods in health disparity research

JS Rao - 2023 - taylorfrancis.com
A health disparity refers to a higher burden of illness, injury, disability, or mortality
experienced by one group relative to others attributable to multiple factors including …

Periodontal disease and birth outcomes: are we missing something?

LG Pessolano, CD Kramer, A Simas… - Current Oral Health …, 2020 - Springer
Abstract Purpose of Review Periodontal disease is a widespread inflammatory disorder
influenced by microbial, genetic, and environmental factors. Dr. Robert J. Genco was a …

The Genetic Architecture of Cervical Length is Shared with Spontaneous Preterm Birth Risk

HM Wolf, BT Webb, JFT Strauss III, R Romero… - medRxiv, 2024 - medrxiv.org
Study Question: Is there a genetic contribution to the change in cervical length during
pregnancy and, if so, how is this related to the known genetic contribution to pregnancy …