[HTML][HTML] Nasal drug delivery devices: characteristics and performance in a clinical perspective—a review

PG Djupesland - Drug delivery and translational research, 2013 - Springer
Nasal delivery is the logical choice for topical treatment of local diseases in the nose and
paranasal sinuses such as allergic and non-allergic rhinitis and sinusitis. The nose is also …

Recommendations for the standardisation of oxytocin nasal administration and guidelines for its reporting in human research

AJ Guastella, IB Hickie, MM McGuinness, M Otis… - …, 2013 - Elsevier
A series of studies have reported on the salubrious effects of oxytocin nasal spray on social
cognition and behavior in humans, across physiology (eg, eye gaze, heart rate variability) …

European position paper on rhinosinusitis and nasal polyps 2012

WJ Fokkens, VI Lund, J Mullol, C Bachert, I Alobid… - Rhinology, 2012 - biblio.ugent.be
The methodology for EPOS2012 has been the same as for the other two productions.
Leaders in the field were invited to critically appraise the literature and write a report on a …

[HTML][HTML] European position paper on rhinosinusitis and nasal polyps 2020

WJ Fokkens, VJ Lund, C Hopkins, PW Hellings, R Kern… - 2020 - observatorio.fm.usp.br
Resumo The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the
update of similar evidence based position papers published in 2005 and 2007 and 2012 …

Corticosteroid nasal irrigations are more effective than simple sprays in a randomized double‐blinded placebo‐controlled trial for chronic rhinosinusitis after sinus …

RJ Harvey, K Snidvongs, LH Kalish… - International forum of …, 2018 - Wiley Online Library
Background Persistent mucosal inflammation in patients with chronic rhinosinusitis (CRS)
often results in ongoing symptoms, recurrence of polypoid mucosa, infective exacerbations …

Engineered nasal dry powder for the encapsulation of bioactive compounds

A Baldelli, MA Boraey, H Oguzlu, A Cidem… - Drug Discovery …, 2022 - Elsevier
Highlights•Particle engineering can be used to design stable dry powder to be nasally
delivered;•Spray and spray freeze drying show the highest control over the properties of dry …

Intranasal dexmedetomidine vs midazolam for premedication in children undergoing complete dental rehabilitation: a double‐blinded randomized controlled trial

SA Sheta, MA Al‐Sarheed… - Pediatric …, 2014 - Wiley Online Library
Background This prospective, randomized, double‐blind study was designed to evaluate the
use of intranasally administered dexmedetomidine vs intranasal midazolam as a …

NAVIGATE I: randomized, placebo-controlled, double-blind trial of the exhalation delivery system with fluticasone for chronic rhinosinusitis with nasal polyps

R Sindwani, JK Han, DF Soteres… - American Journal of …, 2019 - journals.sagepub.com
Background Chronic rhinosinusitis is a common, high-morbidity chronic inflammatory
disease, and patients often experience suboptimal outcomes with current medical treatment …

Fluid residuals and drug exposure in nasal irrigation

RJ Harvey, N Debnath, A Srubiski… - … —Head and Neck …, 2009 - journals.sagepub.com
OBJECTIVE: Topical treatment options in chronic rhinosinusitis (CRS) are growing with our
increased understanding of the inflammatory process. Additives to irrigation devices have …

[HTML][HTML] Visualization and estimation of nasal spray delivery to olfactory mucosa in an image-based transparent nasal model

A Seifelnasr, XA Si, J Xi - Pharmaceutics, 2023 - mdpi.com
Background: Nose-to-brain (N2B) drug delivery offers unique advantages over intravenous
methods; however, the delivery efficiency to the olfactory region using conventional nasal …