Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play a key role in the
regulation of the physiological and pathological signaling within the vasculature. In …

Significance: Hypertension has major health consequences, which is associated with
endothelial dysfunction. Endothelial nitric oxide synthase (eNOS)-produced nitric oxide (NO) …

Reactive oxygen species (ROS) are molecules involved in signal transduction pathways
with both beneficial and detrimental effects on human cells. ROS are generated by many …

Hexahydrocurcumin (HHC), a major metabolite of curcumin, possesses several biological
activities such as antioxidant, anti-inflammation, and cardioprotective properties. This study …

Nobiletin, a citrus flavonoid, exhibits a wide range of biological activities. This study
investigated the effect of nobiletin on vascular dysfunction and remodeling in L-NAME …

Preeclampsia is a pregnancy‑specific disease characterized by hypertension as well as
proteinuria after the 20th week of pregnancy. Animal models are effective tools for studying …

Purpose The present work aimed to study the effect of aqueous extract of large cardamom
(AELC) to prevent vascular remodeling and oxidative stress in Nω-Nitro-L-arginine methyl …

Background Chronic inflammation and oxidative stress play important role in development of
hypertension. Recently, we have reported novel fluorophenyl benzimidazole (FPD) for …

Galangin is a natural flavonoid isolated from ginger, honey and propolis. Aims: To
investigate the effect of galangin on blood pressure, vascular changes, sympathoexcitation …

Tangeretin is a citrus flavonoid that exerts several beneficial effects, including anti-
inflammation, anti-oxidation and neuroprotection. In this study, the aim was to test the effect …