Intranasal delivery of temozolomide-conjugated gold nanoparticles functionalized with anti-EphA3 for glioblastoma targeting

L Wang, S Tang, Y Yu, Y Lv, A Wang, X Yan… - Molecular …, 2021 - ACS Publications
Glioblastoma multiforme (GBM) is a highly lethal and aggressive tumor of the brain that
carries a poor prognosis. Temozolomide (TMZ) has been widely used as a first-line …

Nose-to-brain delivery of temozolomide-loaded PLGA nanoparticles functionalized with anti-EPHA3 for glioblastoma targeting

L Chu, A Wang, L Ni, X Yan, Y Song, M Zhao, K Sun… - Drug …, 2018 - Taylor & Francis
Glioblastoma is the most common malignant brain tumor. Efficient delivery of drugs targeting
glioblastomas remains a challenge. Ephrin type-A receptor 3 (EPHA3) tyrosine kinase …

Benefits and limitations of nanomedicine treatment of brain cancers and age-dependent neurodegenerative disorders

ME Neganova, YR Aleksandrova… - Seminars in Cancer …, 2022 - Elsevier
The treatment of central nervous system (CNS) malignancies, including brain cancers, is
limited by a number of obstructions, including the blood-brain barrier (BBB), the …

Dual-targeted nanomedicines for enhanced tumor treatment

Y Zhu, J Feijen, Z Zhong - Nano Today, 2018 - Elsevier
Based on the overexpression of specific receptors on tumor cells, active targeting
nanomedicines have been developed with the ability to efficiently deliver imaging agents in …

Lactoferrin-and RGD-comodified, temozolomide and vincristine-coloaded nanostructured lipid carriers for gliomatosis cerebri combination therapy

J Zhang, X Xiao, J Zhu, Z Gao, X Lai… - International journal of …, 2018 - Taylor & Francis
Purpose Glioblastoma multiforme (GBM) is the most common malignant brain tumor
originating in the central nervous system in adults. Based on nanotechnology such as …

Delivery of nanoparticles for treatment of brain tumor

C Kang, Y Sun, J Zhu, W Li, A Zhang… - Current Drug …, 2016 - ingentaconnect.com
Background: Malignant brain tumor is a highly challenging disease for diagnosis, treatment,
and management. Cytotoxicity, distribution and the ability to cross blood brain barrier are …

Lactoferrin coated or conjugated nanomaterials as an active targeting approach in nanomedicine

MM Agwa, S Sabra - International Journal of Biological Macromolecules, 2021 - Elsevier
A successful drug delivery to a specific site relies on two essential factors including; efficient
entrapment of the drug within the carrier and successful delivery of drug-loaded nanocarrier …

RGD and interleukin-13 peptide functionalized nanoparticles for enhanced glioblastoma cells and neovasculature dual targeting delivery and elevated tumor …

H Gao, Y Xiong, S Zhang, Z Yang, S Cao… - Molecular …, 2014 - ACS Publications
As the most common malignant brain tumors, glioblastoma multiforme (GBM) was
characterized by angiogenesis and tumor cells proliferation. Dual targeting to …

Tragacanth-mediate synthesis of NiO nanosheets for cytotoxicity and photocatalytic degradation of organic dyes

Z Sabouri, A Akbari, HA Hosseini, M Khatami… - Bioprocess and …, 2020 - Springer
In this study, NiO nanosheets have been manufactured using a co-precipitation approach
that involved the usage of nickel nitrate (Ni (NO 3) 2. 6H 2 O) as the raw material and …

Nanostructured lipid carriers, solid lipid nanoparticles, and polymeric nanoparticles: which kind of drug delivery system is better for glioblastoma chemotherapy?

J Qu, L Zhang, Z Chen, G Mao, Z Gao, X Lai, X Zhu… - Drug …, 2016 - Taylor & Francis
Context: Glioblastoma is a malignant brain tumor originating in the central nervous system.
Successfully therapy of this disease required the efficient delivery of therapeutic agents to …