Glioma targeting and anti-glioma effect of interleukin 13 peptide and RGD peptide dual functionalized nanoparticles

H Gao, Y Hu, Y Xiong, S Zhang, J Yang… - Current …, 2013 - ingentaconnect.com
Targeted nanoparticulated drug delivery systems have gained much attention owing to their
potential in elevating anti-tumor effect and decreasing drug-originated side effects. In this …

转铁蛋白修饰紫杉醇脂质体的制备及其抑瘤作用

靳彩玲, 赵树鹏, 张敏, 王颖, 寇小格, 路平 - 中国药房, 2016 - cqvip.com
目的: 制备转铁蛋白(TF) 修饰紫杉醇(PTX) 脂质体(TF-PTX-LP), 并研究其抑瘤作用. 方法:
采用薄膜分散法制备TF-PTX-LP 并观察其形态; 定性和定量考察肝癌Hep G2 细胞对TF-LP …

Intranasal delivery of nanoparticles

RP Friedrich, I Cicha, R Tietze, H Unterweger… - …, 2022 - Taylor & Francis
Targeted delivery of magnetically labeled stem cells is a promising approach for the
regeneration of functional structures, especially in diseases of the cardiovascular and …

Strategies to better treat glioblastoma: antiangiogenic agents and endothelial cell targeting agents

A Hasbum, J Quintanilla, JAA Jr, MH Ding… - Future Medicinal …, 2021 - Taylor & Francis
Glioblastoma multiforme (GBM) is the most prevalent and aggressive form of glioma, with
poor prognosis and high mortality rates. As GBM is a highly vascularized cancer …

[PDF][PDF] c (RGDyk) 环肽修饰纳米胶束逆转脑胶质瘤对多西他赛的耐药性

吴其隆, 蔡锦华, 徐荷林, 李慧, 赵应征, 陈斌 - 温州医科大学学报, 2019 - xb.wmu.edu.cn
目的: 构建c (RGDyk) 环肽修饰的纳米胶束包载多西他赛(DTX), 体外评价其逆转人脑胶质瘤U87
细胞对DTX 耐药性. 方法: 以泊洛沙姆-188 (PL-188) 为原材料, 经琥珀酸酐羧基化后, 键合c …

[HTML][HTML] Development of synthetic of peptide-functionalized liposome for enhanced targeted ovarian carcinoma therapy

H Wu, L Yao, J Mei, F Li - International Journal of Clinical and …, 2014 - ncbi.nlm.nih.gov
In this study, we report an active targeting liposomal formulation directed by a novel peptide
(T7) that specifically binds to the transferrin receptor (TfR) overexpressed on ovarian …

Glioblastoma: State of the Art of Treatments and Applications of Polymeric and Lipidic Nanomedicines

V Sgarbi, JT Duskey, I Ottonelli, F Da Ros… - Nanotherapy for Brain …, 2021 - Springer
Glioblastoma multiforme (GBM) is one of the most devastating tumors affecting more than 5
in 100,000 people. Unfortunately, its diagnosis is often discovered in late stages and is …

脑肿瘤靶向递药策略及其研究进展

刘瑜, 魏晓丽, 应曼, 黄志刚, 陆伟跃 - 药学进展, 2016 - cqvip.com
脑肿瘤严重威胁人类生命, 其特有的屏障结构阻碍了药物有效进入. 以脑胶质瘤为例,
对现有脑肿瘤主要靶向策略作一简要综述, 并提出了脑肿瘤靶向递药的新理念 …

[PDF][PDF] 乙肝病毒X 蛋白与肝癌的关系…………………………………………… 蔡平平, 黄建炜, 苏成豪, 崔秀灵, 许瑞安(165)

何阳, 刘阳光, 丁寄葳, 李晓宇, 岑山, 周金明, 杨苏… - 药学学报, 2016 - researchgate.net
肿瘤已成为危害人类健康和生命的第二大疾病. 尽管已有多种抗肿瘤药物上市,
但是由于肿瘤靶向性不佳, 肿瘤内蓄积能力较差, 使得抗肿瘤效果不尽如人意 …

[PDF][PDF] Biomaterials Advances

T Zwain, JE Alder, S Zwayen, A Shaw, AJ Burrow… - researchgate.net
ABSTRACT A major obstacle for chemotherapeutics in Glioblastoma (GB) is to reach the
tumour cells due to the presence of the blood-brain barrier (BBB) and chemoresistance of …