Mitochondrial transplantation attenuates traumatic neuropathic pain, neuroinflammation, and apoptosis in rats with nerve root ligation

CC Huang, HY Chiu, PH Lee, SY Fang… - Molecular …, 2023 - journals.sagepub.com
Traumatic neuropathic pain (TNP) is caused by traumatic damage to the somatosensory
system and induces the presentation of allodynia and hyperalgesia. Mitochondrial …

Mitochondrial transplantation for the treatment of cardiac and noncardiac diseases: mechanisms, prospective, and challenges

X Wang, Z Liu, L Zhang, G Hu, L Tao, F Zhang - Life Medicine, 2024 - academic.oup.com
Mitochondrial transplantation (MT) is a promising therapeutic strategy that involves
introducing healthy mitochondria into damaged tissues to restore cellular function. This …

[HTML][HTML] Promising Therapeutic Strategies Targeting Mitochondria in Kidney Diseases: From Small Molecules to Whole Mitochondria

AP Jiménez-Uribe, J Pedraza-Chaverri - Future Pharmacology, 2022 - mdpi.com
Kidney function highly depends on mitochondria, organelles that regulate different metabolic
pathways. Mitochondria-altered function and structure are present during acute kidney injury …

Mitochondrial transplantation: A promising therapy for mitochondrial disorders

Q Jiao, L Xiang, Y Chen - International Journal of Pharmaceutics, 2024 - Elsevier
As a vital energy source for cellular metabolism and tissue survival, the mitochondrion can
undergo morphological or positional change and even shuttle between cells in response to …

[HTML][HTML] Mitochondrial transfer-a novel promising approach for the treatment of metabolic diseases

R Chen, J Chen - Frontiers in Endocrinology, 2024 - frontiersin.org
Metabolic disorders remain a major global health concern in the 21st century, with
increasing incidence and prevalence. Mitochondria play a critical role in cellular energy …

A new hope: mitochondria, a critical factor in the war against prions

K Zambrano, D Barba, K Castillo, P Robayo, E Arizaga… - Mitochondrion, 2022 - Elsevier
Prion diseases encompass a group of incurable neurodegenerative disorders that occur due
to the misfolding and aggregation of infectious proteins. The most well-known prion …

Reviewing the suitability of mitochondrial transplantation as therapeutic approach for pulmonary hypertension in the era of personalized medicine

GJ Maarman - … Journal of Physiology-Lung Cellular and …, 2022 - journals.physiology.org
Pulmonary hypertension (PH) is a fatal disease, defined as a mean pulmonary artery
pressure≥ 25 mmHg. It is caused, in part, by mitochondrial dysfunction. Among the various …

[HTML][HTML] Mitochondria Transplantation Promotes Corneal Epithelial Wound Healing

D Raz, K Ben-Yaakov, M Levi, M Bertolin… - … & Visual Science, 2024 - tvst.arvojournals.org
Purpose: The integrity of the corneal epithelium is essential in maintaining normal corneal
function. Conditions disrupting the corneal epithelial layer range from chemical burns to dry …

Can mitochondria brown the lower-limb adipocytes?

IP Doulamis, A Tzani - Molecular Therapy Methods & Clinical Development, 2024 - cell.com
Lower limb ischemia reperfusion injury (IRI) is commonly observed in the clinical setting
either in an unexpected urgent manner such as embolism, acute thrombosis, and trauma or …

[HTML][HTML] Nonequilibrium thermodynamics and mitochondrial protein content predict insulin sensitivity and fuel selection during exercise in human skeletal muscle

R Zapata Bustos, DK Coletta, JP Galons… - Frontiers in …, 2023 - frontiersin.org
Introduction: Many investigators have attempted to define the molecular nature of changes
responsible for insulin resistance in muscle, but a molecular approach may not consider the …